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43.670  Articles
1 of 4.367 pages  |  10  records  |  more records»
Drug-drug interactions (DDIs) are responsible for many serious adverse events; their detection is crucial for patient safety but also very challenging. In recent years, several drugs have been withdrawn from the market due to interaction related Adverse E... see more

Computer technology is an integral part of modern research. Most undergraduate pharmacy students are not aware of the use of these techniques in the drug design process. Understanding drug-target interactions plays a vital role in the drug design process,... see more

The prediction of Compound-Protein Interactions (CPI) is an essential step in drug-target analysis for developing new drugs. Therefore, it needs a good incentive to develop a faster and more effective method to predicting the interaction between compound ... see more

In this work, a bio-composite sorbent, alginate incorporated graphene oxide (Alg/GO) is prepared for the micro solid phase extraction of non-steroidal anti-inflammatory drugs (NSAIDs) from water samples. The sorbent was prepared in a suspended solution fo... see more

While there are existing databases that curate only drug, target, or pathway data for instance, none of these alone are exhaustive. The Drug Gene Pathway (DRUGPATH) meta database was created as a response to the complex treatment required for various dise... see more

ABSTRACTPharmacodynamical studies showed that most drugs elicit their effects by acting on 3 kinds of protein molecules known as receptors, enzymes or transporters. Although their detail properties had not been explained for decades the roles of transport... see more

Drug repurposing is a fast and consolidated approach for the research of new active compounds bypassing the long streamline of the drug discovery process. Several drugs in clinical practice have been reported for modulating the major Hippo pathway’s... see more

Non-small cell lung cancer (NSCLC) has evolved into the deadliest in the present scenario. The progression of NSCLC is mainly due to the dysregulation of the tyrosine kinase family's epidermal growth factor receptor (EGFR). Thus, EGFR has been widely stud... see more

Drug-drug interactions (DDIs) is defined as the alteration of efficacy and toxicity of some drugs in the presence of other drugs. In the treatments of bronchopneumonia in outpatient settings, there is a lack of documentation of DDIs. This study was aimed ... see more

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