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2.170.441  Articles
1 of 217.045 pages  |  10  records  |  more records»
Posisi pertama untuk kejadian dan mortalitas kanker paru di dunia saat ini masih menjadi tantangan untuk menemukan dan mengembangkan terapi potensial bagi pasien kanker paru. Pemahaman pada tingkat molekular mengenai progres tumor pada kanker sangat diper... see more

BackgroundPeritoneal adhesions (PAs) are generally described as fibrous bands between intra-abdominal organs following an abdominal surgical operation. The definitive treatments of PAs are currently ineffective yet. Hypoxia-mesenchymal stem cells (H-MSCs)... see more

Full-thickness wound healing is a complex process requiring a well-orchestrated mechanism of various factors, including cytokines, particularly interleukin (IL)-10 and transforming growth factor (TGF)-ß. IL-10 and TGF-ß act as robust anti-inflammatory cyt... see more

Pertumbuhan dan perkembangan kanker dapat dipengaruhi oleh perubahan jalur pensinyalan. Dua pensinyalan utama yang mengalami perubahan pada kanker adalah pensinyalan Wnt dan TGF-ß. Pensinyalan Wnt memiliki peran dalam proliferasi dan apoptosis sel, sedang... see more

Paper description:Anormal TGF-ß expression is observed at different stages of colon carcinoma. Carbonic anhydrase III (CAIII) is involved in acute myeloid leukemia and hepatic carcinoma.TGF-ß downregulated CAIII gene expression at the level of mRNA and pr... see more

BACKGROUND: Mesenchymal stem cells (MSCs) may serve as immunoregulators by producing various anti-inflammatory molecules. Under sufficient level of TNF-a, MSCs become activated and adopt immune-suppressive phenotype (MSCs type-2) by releasing various anti... see more

BACKGROUND: Papillary thyroid carcinoma (PTC) accounts for 80% of the thyroid malignancies that are characterised by slow growth and an excellent prognosis. Over-expression of SMAD4 protein restores TGF-ß signalling, determines a strong increase in anti-p... see more

Purpose: Studies on odontogenic tumors have identified various molecular dysfunctions involved on their development, and some mechanisms such as angiogenesis and matrix modulation, are useful means of investigating the differences in biologic be... see more

The importance of miRNAs in the progression of prostate cancer (PCa) has further been supported by the finding that miRNAs have been identified as potential oncogenes or tumor suppressors in PCa. Indeed, in eukaryotes, miRNAs have been found to regulate a... see more

1 of 217.045 pages  |  10  records  |  more records»