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3.906  Articles
1 of 392 pages  |  10  records  |  more records»
Full-thickness wound healing is a complex process requiring a well-orchestrated mechanism of various factors, including cytokines, particularly interleukin (IL)-10 and transforming growth factor (TGF)-ß. IL-10 and TGF-ß act as robust anti-inflammatory cyt... see more

The interaction between genetic factors, blood glucose and hypertension plays a role in the onset of diabetic kidney disease (DKD) in type II diabetes mellitus (T2DM). Genetic variation of TGF-ß1 is associated with renal complication in T2DM with varying ... see more

Posisi pertama untuk kejadian dan mortalitas kanker paru di dunia saat ini masih menjadi tantangan untuk menemukan dan mengembangkan terapi potensial bagi pasien kanker paru. Pemahaman pada tingkat molekular mengenai progres tumor pada kanker sangat diper... see more

Pertumbuhan dan perkembangan kanker dapat dipengaruhi oleh perubahan jalur pensinyalan. Dua pensinyalan utama yang mengalami perubahan pada kanker adalah pensinyalan Wnt dan TGF-ß. Pensinyalan Wnt memiliki peran dalam proliferasi dan apoptosis sel, sedang... see more

El Factor de crecimiento transformante ß (TGF-ß) es una citocina pleiotrópica implicada en distintas condiciones patológicas, como desórdenes autoinmunes, alergias y en los últimos años, en el cáncer. Esta citocina ejerce efectos supresores de tumores que... see more

BackgroundPeritoneal adhesions (PAs) are generally described as fibrous bands between intra-abdominal organs following an abdominal surgical operation. The definitive treatments of PAs are currently ineffective yet. Hypoxia-mesenchymal stem cells (H-MSCs)... see more

Paper description:Anormal TGF-ß expression is observed at different stages of colon carcinoma. Carbonic anhydrase III (CAIII) is involved in acute myeloid leukemia and hepatic carcinoma.TGF-ß downregulated CAIII gene expression at the level of mRNA and pr... see more

BACKGROUND: Mesenchymal stem cells (MSCs) may serve as immunoregulators by producing various anti-inflammatory molecules. Under sufficient level of TNF-a, MSCs become activated and adopt immune-suppressive phenotype (MSCs type-2) by releasing various anti... see more

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