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11.139  Articles
1 of 1.115 pages  |  10  records  |  more records»
Chronic Myeloid Leukemia (CML) is one of leukemias characterized by abnormal growth of myeloid cells in bone marrow. The Philadelphia chromosome is diagnostic parameter for CML. This chromosome is t(9;22) (q32;q21), a translocation chromosome 9 and 22 rel... see more

Introduction: Ocular involvement in patients with CMML is rarely reported, owing in part to the fact that the severe illness faced by many of these patients limits the feasibility of ocular examinations. Nevertheless, post-mortem examination of the eyes o... see more

Objective: To determine left ventricular function of patients with Chronic Granulocytic Leukemia in Chronic Phase (CGL-CP) who received imatinib and nilotinib by using Global Longitudinal Strain (GLS) examination.Methods: This was a descriptive study invo... see more

Until recently, the main goal of chronic myeloid leukemia therapy was disease control with the best overall survival, which required lifelong treatment. However, currently, the treatment-free remission concept is becoming an important goal in clinica... see more

Pediatric chronic myeloid leukemia (CML) is a hematopoietic malignancy, treated by tyrosine kinase inhibitor (TKI). Previously, imatinib resistance in CML was treated with nilotinib as a second line. However, in Indonesia, where the options of TKIs are li... see more

Achieving a deep molecular response (MR4) is a prerequisite for imatinib therapy discontinuation in patients with chronic myeloid leukemia (CML). 313 patients with a chronic phase of CML at the age from 18 to 80 years (Me = 42 years) were examined to det... see more

Chronic lymphocytic leukemia (CLL) is hematopoietic malignancy involving clonal proliferation and accumulation of morphologically mature yet functionally incompetent B-lymphocytes in blood, lymphoid tissue and, less commonly, extralymphatic organs. Despit... see more

BACKGROUND: Emergence of additional chromosomal abnormalities (ACAs) in chronic myeloid leukemia (CML) is associated with disease progression to advanced phases and reflects the genetic instability of CML.AIM: Is to evaluate the frequency of ACAs in chron... see more

Pediatric chronic myeloid leukemia (CML) is a hematopoietic malignancy, treated by tyrosine kinase inhibitor (TKI). Previously, imatinib resistance in CML was treated with nilotinib as a second line. However, in Indonesia, where the options of TKIs are li... see more

1 of 1.115 pages  |  10  records  |  more records»