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Carleigh Robertson    

Multiple sclerosis (MS) is a complex disease characterized by autoimmune demyelination of the myelin sheath of the central nervous system. Varying degrees of disability result from disruptions in neural, physical, and psychological processes. No clear ca... see more


Brittany R. Silverman and Jiaqi Shi    

Pancreatic cancer is one of the most aggressive human cancer types with a five-year survival less than 7%. Emerging evidence revealed that many genetic alterations in pancreatic cancer target epigenetic regulators. Some of these mutations are driver muta... see more


Donata Orioli and Elena Dellambra    

Skin undergoes continuous renewal throughout an individual’s lifetime relying on stem cell functionality. However, a decline of the skin regenerative potential occurs with age. The accumulation of senescent cells over time probably reduces tissue r... see more

Revista: Cells

Brooke D. Paradise, Whitney Barham and Martín E. Fernandez-Zapico    

Pancreatic cancer has one of the highest mortality rates among all types of cancers. The disease is highly aggressive and typically diagnosed in late stage making it difficult to treat. Currently, the vast majority of therapeutic regimens have only modes... see more

Revista: Cancers

Ana Luiza Sprotte Mira, Kathleen Lietke Kolb, Larissa Schneider, Eduardo Delabio Auer, Priscila Ianzen dos Santos, Guilherme Luiz da Rocha, Vale´ria Bumiller Bini, Gabriela Canalli Kretzschmar, Sheila Coelho Soares Lima, Angelica Beate Winter Boldt (Autor)    

Mennonites present cc. 500 years genetic isolation and three bottleneck events that reduced their genetic diversity. In order to identify (epi)genetic markers for metabolic syndrome (MS), we used a modified version of the Brazilian National Health Survey... see more

Revista: Arquivos do Mudi