30 articles in this issue
Santi Syafril, Dharma Lindarto, Aznan Lelo, Rosita Juwita Sembiring, Awaluddin Saragih (Author)
BACKGROUND: Defects in post-receptor insulin signalling are the major cause of insulin resistance in type 2 diabetes mellitus (T2DM).AIM: This study aimed to investigate the correlations between insulin receptor substrate (IRS)-1 with phosphoinositide 3-k... see more
Vivi Sofia, Moch Saiful Bachri, Rizki Rahmadian (Author)
BACKGROUND: Pharmacological therapy in the management of OA causes many new health problems due to side effects caused by long-term use of drugs, such as long-term use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) will cause gastric ulcers and impaire... see more
Nour El Hoda S. Ismael, Rasha A. Khairy, Suzan M. Talaat, Fatima A. Abd El-Fattah (Author)
BACKGROUND: Breast carcinoma ranks the first among malignant tumours in females and is the chief cause of cancer-related mortality. Androgen in implicated in the induction of proliferation and growth of mammary cells through binding to their corresponding... see more
Dumawan Harris Parhusip, Gontar Alamsyah Siregar, Leonardo Basa Dairi (Author)
BACKGROUND: Gastritis was defined as the histological presence of gastric mucosal inflammation. One of the most common aetiology was H. pylori. Gastrin-17 was a hormone that was secreted by G cells. H. pylori infection induced increased in gastrin-17 in g... see more
Endrinaldi Endrinaldi, Eryati Darwin, Nasrul Zubir, Gusti Revilla (Author)
BACKGROUND: Osteoarthritis (OA) is one of the most common diseases among the elderly. OA occurs due to an imbalance between degradation and synthesis in articular joint tissue, causing changes in joint components such as cells, matrices and molecular prod... see more
Ahmed Hasanin, Karim Hussein Mourad, Inas Farouk, Sherin Refaat, Ahmed Nabih, Sabah Abdel Raouf, Hala Ezzat (Author)
BACKGROUND: A growing interest had been paid to goal-directed fluid therapy (GDT) in abdominal surgery; however, its impact on the respiratory profile was not well investigated.AIM: We evaluated the impact of GDT on postoperative extravascular lung water ... see more
Miras Mugazov, Yermek Turgunov, Dinar Kaliyeva, Dmitriy Matyushko, Zhandos Koishibayev, Dinara Omertayeva, Aidyn Nurbekov, Leyla Koishibayeva, Asylkhan Alibekov (Author)
AIM: The purpose of this study was to determine the level of significance of markers in the development of intra-abdominal hypertension in patients with acute surgical diseases of the abdominal cavity.METHODS: The authors surveyed 100 patients who were mo... see more
Bhupendra Verma, Amrita Singh (Author)
INTRODUCTION: Dobutamine stress echocardiography (DSE) and myocardial perfusion scan are the commonly used modalities to detect viable myocardium. DSE is comparatively cheaper and widely available but has a lower sensitivity.AIM: We aimed to compare contr... see more
Hysni Ismaili, Levent Ismaili, Meral Rexhepi (Author)
BACKGROUND: Patients with rheumatoid arthritis (RA) are at increased risk of cardiovascular disease (CVD). Lipid changes related to inflammation have been described in RA. Methotrexate (MTX) treatment is effective in controlling inflammation and decreasin... see more
Endy Juli Anto, Sony Eka Nugraha (Author)
BACKGROUND: Helminthiasis in school-aged children potentially causing physical growth and intellectual development retardation. Trichuriasis was the most common type of helminthiasis in children.AIM: To investigated the efficacy and side effects of albend... see more
Alireza Alehashemi, Zahra Mostafavian, Najmeh Dareini (Author)
BACKGROUND: One of the typical complaints in females with multiple sclerosis (MS) is Sexual dysfunction (SD).AIM: This study aimed to compare the sexual function of women with and without MS and to recognise factors that possibly related to sexual dysfunc... see more
Hendrika Andriana Silitonga, Jekson Martiar Siahaan, Endy Juli Anto (Author)
BACKGROUND: Obesity is a multifactorial disease that is dangerous and is a factor in the emergence of serious diseases such as dyslipidemia, stroke, coronary heart disease and others. In Type 2 Diabetes Mellitus (T2DM) patients there is a disorder of lipi... see more
Valentina Cvejoska-Cholakovska, Mirjana Kocova, Vesna Velikj-Stefanovska, Emilija Vlashki (Author)
BACKGROUND: Association of asthma and obesity has been demonstrated in numerous epidemiological studies. However, the underlying mechanisms of the association are not well understood. Both conditions are characterised by chronic tissue inflammation, which... see more
Nevyana Veleva, Violeta Chernodrinska (Author)
BACKGROUND: With the establishment of laser photocoagulation as a standard treatment modality for prethreshold retinopathy of prematurity (ROP), a dramatic reduction of cases with ROP blindness and severe visual impairment have been reported. In the same ... see more
Sherin Refaat, Ashraf Ali Mawgood, Mohamed Al Sonbaty, Maged Gamal, Abdelrazik Ahmed (Author)
BACKGROUND: Advancement in minimally invasive laparoscopic surgeries make it one of the best choices for both the surgeon and the patient. The anesthesiologist had to improve the techniques used to control post-operative pain.AIM: In this study, we hypose... see more
Moushira Erfan Zaki, Walaa Basha, Rasha Nazih Yousef, Mona Awad (Author)
BACKGROUND: Obesity is a major factor in the development of several sub-clinical anomalies. Insulin resistance (IR) is associated with obesity. Vascular endothelial growth factor (VEGF) plays a significant role in inflammation and vascular neogenesis. How... see more
Ahmed Abdalla Mohamed, Nadia Gameel Elsharkawi, Osama Ismail Zaid, Ahmed Farag Mohamed, Nashwa Nabeel Mohamed, Michael Wahib Wadeed, Adham Feteha Tawfik, Amr Abdelmonam Abdelaziz Mostafa Elkatatny (Author)
AIM: Comparing the effects of Albumin 5% versus Ringer's lactate on blood loss and coagulation after vascular surgery usingMETHODS: In this randomised study, 60 patients, aged (18-60 years) ASA physical status (I-III) undergoing vascular surgery were incl... see more
Ruby Kurniawan, I Kadek Suarca, I Wayan Bikin Suryawan (Author)
BACKGROUND: Goldenhar syndrome is a multiple congenital disorder with classic characteristics regarding the face, eyes, ears. The incidence of this case is between 1:3.500 to 1:5.600. Early detection and good management can have good outcomes. A newborn w... see more
Ivanka Temelkova, Georgi Tchernev (Author)
BACKGROUND: Neurofibromatosis is a genetic disease with an autosomal dominant type of inheritance. It is a multisystem disease in which, besides skin manifestations, there is a possibility for the involvement of other organs and systems, and an atypical v... see more
Frendy Wihono, Yacobda Sigumonrong (Author)
BACKGROUND: Traumatic penile amputation is an uncommon surgical emergency with various etiologies, carrying major functional and psychological consequences concerning the patient’s overall quality of life. Regardless of the aetiology, penile amputation re... see more
Ni Putu Sriwidyani, Ni Luh Gede Sagita Dewi, I Nyoman Golden, I Putu Eka Widyadharma (Author)
BACKGROUND: Cryptococcus is a common cause of opportunistic infection in HIV-positive patients. While the incidence of this disease has decreased in AIDS-associated cases, cryptococcal infection in immune-competent person has been increased.CASE PRESENTAT... see more
Putu Anda Tusta Adiputra, I Wayan Sudarsa (Author)
BACKGROUND: Squamous cell carcinoma (SCC) of the breast is very unusual. Thoraco-abdominal (TA) flap is a simple flap, and it is a rotation advancement fasciocutaneous flap. Here, we present a case of using TA flap for chest wall reconstruction in quick i... see more
Shereen Essameldin Fahim, Mostafa Abdelhamid Mostafa, Mohsen Hussein Abi-Elhassan, HebatAllah Mohamed Taher (Author)
BACKGROUND: Delivering sufficient intensity output of curing lights is mandatory to ensure optimum cure and clinical success of bulk-fill resin composite restorations and to avoid undesirable clinical outcomes.AIM: To evaluate the effectiveness of using l... see more
Aida Mossaad, Tarek El Badry, Moustapha Abdelrahman, Ahmad Abd Elazeem, Wael Ghanem, Susan Hassan, Nahed Adly, Wael Shawkat (Author)
BACKGROUND: Cleft lip and palate CLP is a frequent congenital malformation that manifests in several varieties including unilateral or bilateral anomalies due to either genetic or acquired causes. Alveolar cleft graft ACG remains controversial as regard t... see more
Sultan A. Almalki (Author)
AIM: This study aimed to assess the influence of motivation on academic performance among dental undergraduate students.METHODS: A cross-sectional study was carried out among a sample of 187 undergraduate dental students from the main dental colleges in t... see more
Henni Cintya, Jansen Silalahi, Effendy De Lux Putra, Rikson Siburian (Author)
BACKGROUND: Nitrosamine is a carcinogen and the maximum level in processed meat products set by WHO.AIM: The purpose of this study was to determine nitrosamine levels in meat products in Medan City and compared nitrosamine levels with standards set by WHO... see more
Svetlana Jangildinova, Yelena Tatina, Gulzhan Kaliyeva, Kuttykyz Kuvatbaeva, Nursaya Beygam (Author)
AIM: We aimed to study the influence of adverse environmental factors on molecular-cellular processes in the population living in the Aral Sea region.METHODS: Extracellular RNA (ecRNA) and ecDNA were determined in blood. We obtained the ejaculate of the s... see more
Pelumi E. Oguntunde, Hilary I. Okagbue, Omoleye A. Oguntunde, Oluwole A. Odetunmibi (Author)
BACKGROUND: Noise pollution has become a major environmental problem leading to nuisances and health issues.AIM: This paper aims to study and analyse the noise pollution levels in major areas in Ota metropolis. A probability model which is capable of pred... see more
Anila Cake, Joana Mihani, Gentian Stroni, Rovena Stroni, Afrim Avdaj (Author)
BACKGROUND: Healthcare workers have a high risk of professional exposure, especially in developing countries.AIM: This paper aims to determine whether there is a link between knowledge and HIV prophylaxis on HIV prevention in Albanian healthcare system em... see more
Shofian Syarifuddin, Azizah Nasution, Aminah Dalimunthe, - Khairunnisa (Author)
AIM: To analyse the characteristics, and analyse the impact of pharmacist intervention on quality of life (QOL) outpatients with type 2 diabetes mellitus (T2DM).METHODS: This six-month analytical cohort study was conducted by assessing the patients’ chara... see more