30 articles in this issue
Pramudji Hastuti, Tasmini Tasmini, Rizki Fajar Utami, Meirlin Rambu Kaita Riwa, Steven Steven, Ahmad Hamim Sadewa (Author)
BACKGROUND: Obesity is considered associated with an increase of resistin levels that plays a role in the regulation of energy and maintaining fasting blood glucose. Polymorphism of resistin is thought to be correlated with the levels of resistin and insu... see more
Kiril Mihajlov, Aneta Andreska, Nadica Ristovska, Tatjana Grdanoska, Elena Trajkovska-Dokic (Author)
BACKGROUND: Clostridium difficile is a major nosocomial pathogen. In Europe, this bacterium is mostly characterised by PCR ribotyping. Most of the Clostridium difficile infections (CDI) are treated with vancomycin or metronidazole, although prolonged anti... see more
Liudmila Ivanovna Babaskina, Tatiana Mikhailovna Litvinova, Dmitrii Vladimirovich Babaskin, Mikhail Valentinovich Kiselevsky, Olga Vladimirovna Savinova, Elizaveta Aleksandrovna Winter (Author)
BACKGROUND: The spread of phytocomplex application and justification of its selective effects on tumour cells (mainly due to the presence of flavonoids) require research of its cytotoxic and immunomodulatory activity.AIM: The goal was to study the direct ... see more
Afdal Afdal, Eryati Darwin, Yanwirasti Yanwirasti, Rizal Hamid (Author)
BACKGROUND: Prostate hyperplasia and prostate cancer are two of the most common pathological condition of the prostate to be found on male. Both of these diseases share common pathogenesis involving inflammation of prostatic tissues. Chronic inflammation ... see more
Dessy Arisanty, Wirsma Arif Harahap, Daan Khambri, Rony Rustam, Gestina Aliska, Afifatul Achyar, Juane Plantika Menra (Author)
BACKGROUND: The expression of a gene is a process that conveys information of genes to synthesise gene product is functional. Alterations of the molecular biology in breast cancer are very complex because of many factors play a role in the tumorigenesis. ... see more
Ali Hussein Mohammed Ali, Alaa Qasim Yahya, Haider Latteef Mohammed (Author)
BACKGROUND: The rapidly growing knowledge regarding factors controlling tumour growth, with the new modalities of therapy acting on the biological activity of the tumours draw the attention of most cancer researches nowadays and represent a major focus fo... see more
Gorica Popova, Katerina Boskovska, Ivana Arnaudova-Danevska, Olga Smilevska-Spasova, Tatjana Jakovska (Author)
BACKGROUND: The clinical relevance of specimens from the lower airways is often debatable. However, they are most commonly examined for diagnosing lower respiratory tract infections (LRTIs).AIM: This study aimed to determine the diagnostic value of sputum... see more
Bugis Mardina Lubis, Sjarif Hidajat Effendi, Ratna Akbari Ganie, Oke Rina Ramayani (Author)
BACKGROUND: Neuregulin (NRG) 1 plays an important role in the development of various organ systems in human. Single nucleotide polymorphisms rs35753505 C/Tof the gene encoding NRG1 evident as allele C and T with genotypes of CT, CC, and TT are believed to... see more
Susy Tjahjani, Yonathan Biantoro, Rita Tjokropranoto (Author)
BACKGROUND: Drug resistance to malaria is still a problem in various regions, and there have even been developments in resistance to the ACTs (artemisinin-based combination therapies) as standard antimalarial drugs included to artemisinin’s partner drugs.... see more
Meike Rachmawati, Herry Yulianti, Bethy S. Hernowo, Sri Suryanti, Indra Wijaya, Nur Rahadiani, Didik S. Heriyanto, Irianiwati Irianiwati (Author)
BACKGROUND: Colorectal Adenocarcinoma (ADCCR) is the third most cancer not only in the world but also in Indonesia. There were 623 cases of ADCCR at Dr Hasan Sadikin hospital within 2015-2017. Both KRAS and TP53 mutation are known as genes which involve i... see more
Ali Habibi, Abbas Alipour, Afshin Gholipour Baradari, Abdolmajid Gholinataj, Mohammad Reza Habibi, Saloumeh Peivandi (Author)
BACKGROUND: Caesarean section is one of the commonest gynaecological surgeries. AIM: Given the importance of pain relief after caesarean section surgery as well as contradictions in the studies conducted on intravenous lidocaine analgesic effects, this st... see more
Malgorzata Radon-Pokracka, Beata Adrianowicz, Magdalena Plonka, Paulina Danil, Magdalena Nowak, Hubert Huras (Author)
AIM: The study aimed to investigate the association between advanced maternal age (AMA) and the risk of adverse maternal, perinatal and neonatal outcomes about parity in singleton pregnancies.METHODS: We retrospectively analysed 950 women who gave birth i... see more
Deasy Hendriati, Elemeida Effendy, Mustafa Mahfud Amin, Vita Camellia, Muhammad Surya Husada (Author)
BACKGROUND: Schizophrenia is a severe mental disorder that is multi-causative and multi-factor, generally affecting about 1% of the population. The elevation level of brain-derived neurotrophic factor (BDNF) offers several protections from other neurodege... see more
Dyah Kanya Wati, Putu Cintya Denny Yuliyatni, I Made Krisna Dinata, Gusti Ayu Putu Nilawati, I Gede Raka Widiana, Ida Bagus Ramajaya Sutawan, I Gusti Ngurah Putu Mandela Agatha Sunantara (Author)
BACKGROUND: Mortality and morbidity in an adult will be reduced by controlling hypertension from an early age. Uncontrolled blood pressure since children can contribute to diseases such as heart disease, organ damage, and decreased quality of life. As cha... see more
Yousry Moustafa, Hala G. El Nady, Maha M. Saber, Ola A. Dabbous, Terez Boshra Kamel, Khaled G. Abel-Wahhab, Sara Fawzy Sallam, Dina A. Zaki (Author)
BACKGROUND: Allergic rhinitis (AR) represents one of the most common global health problems with seriously increasing incidence over the last decades. The goal of the treatment of rhinitis is to prevent or reduce the symptoms caused by the inflammation of... see more
Sara Gaber, Emad Saleh, Somaya Elshaikh, Rafaat Reyad, Mohamed Elramly, Ismail Mourad, Mohamed Abdel Fattah (Author)
BACKGROUND: Post-thoracotomy pain syndrome (PTPS) can be challenging to treat. AIM: This study aimed to evaluate the efficacy of perioperative pregabalin in the prevention of acute and chronic post-thoracotomy pain. METHODS: Sixty patients scheduled for t... see more
Mohamed Alkhatim Alsammani, Khalid Nasralla, Sumeya A. Kheiri, Zaheera Saadia, Mohamed Abdelgadir Shaaeldin, Ali Osman Ali (Author)
AIM: To determine the frequencies of intrapartum fetal and maternal complications in women without the identified prenatal risk factorMETHODS: We conducted a prospective cross-sectional investigation from January to June 2017 at Khartoum North Maternity H... see more
Cokorda Agung Wahyu Purnamasidhi, Ketut Suega, I Made Bakta (Author)
BACKGROUND: Non-Hodgkin Lymphoma (NHL) is a malignant haematological disease originates in the lymphocytes, caused by an abnormality in lymphocytes development which forms a tumour and may become cancer. Chemotherapy is the main treatment modality for agg... see more
AA Mas Putrawati Triningrat, Ni Made Wasiastiti Budi, IGAM Juliari, Ni Made Ayu Surasmiati, IGA Ratna Suryaningrum, Siska Siska (Author)
BACKGROUND: In HIV-infected patient who accompanied by syphilis often difficult to diagnose and difficult to treat. The aim is to diagnostics understanding and to optimise the management and response therapy in patients with neuroretinitis syphilis in HIV... see more
Martina Savovska, Sinisa Stojanoski, Nevena Manevska (Author)
BACKGROUND: Peripheral resistance to thyroid hormones is a type of unresponsiveness of the peripheral cells or tissues to FT3 and/or FT4. Generalised resistance to thyroid hormones affects the pituitary gland and most of the peripheral tissues. Selective ... see more
Meral Rexhepi, Elizabeta Trajkovska, Kazimir Koprivnjak (Author)
BACKGROUND: Fibroepithelial cervical polyps (FEPs) are benign growths protruding from the inner surface of the cervix. They are typically asymptomatic, but a very small minority can undergo malignant change. Giant cervical polyps with a size greater than ... see more
A. A. Ayu Suryapraba, Ni Made Susilawathi, I Wayan Niryana (Author)
BACKGROUND: Central nervous system (CNS) tuberculosis (TB) can manifest as meningitis, abscess, tuberculoma or other manifestations. CNS TB is a rare TB complication, and its diagnosis remains a challenge since it has clinical and imaging features that re... see more
Adegbenro Omotuyi John Fakoya, Emilio Aguinaldo, Natalia M. Velasco-Nieves, Zachary T. Vandeveer, Nannette Morales-Marrietti, Shannon Matthew, Abayomi Gbolahan Afolabi, Thomas McCracken (Author)
BACKGROUND: Variations in human anatomy have been associated with numerous clinical correlations that may affect patient care. In this article, we present a unique variation of the medial cord of the brachial plexus about the axillary artery and subscapul... see more
Tomike I. Olawande, Mofoluwake P. Ajayi, Emmanuel O. Amoo, Charles T. Iruonagbe (Author)
BACKGROUND: The major challenge faced in Nigeria regarding the care of people living with mental illness are a stigma, caregiver burden and financial aid. This has led to high premature deaths and has also hindered the attainment of Sustainable Developmen... see more
Mansour Ranjbar, Masoumeh Neishabouri, Mohammad Ali Heidari Gorji (Author)
BACKGROUND: In recent decades, managing health-service systems has faced multiple challenges. Identifying and resolving these challenges promote the efficiency and effectiveness of hospital activities. AIM: The present study aimed to explore the human fac... see more
Ebtissam M. Salah El Din, Thanaa M. Rabah, Ammal M. Metwally, Maysa S. Nassar, Mona A Elabd, Ashraf Shalaan, Wafaa Kandeel, Lobna A. El Etreby, Sanaa Y. Shaaban (Author)
BACKGROUND: The first two years of life constitute a critical period of rapid change. The events during this phase prepare the child for subsequent developmental competency.AIM: To determine the potential risk factors that affect an infant’s cognitive dev... see more
Anthonia Adenike Adeniji, Adewale Omotayo Osibanjo, Tunde Charles Iruonagbe, Tomike Olawande, Ayodotun Stephen Ibidunni, Maxwell Ayodele Olokundun (Author)
BACKGROUND: In the Nigerian, like most developing economies’, health sector, employees’ perceptions about treatments of diversity are crucial not only to their satisfaction with the job but equally to their commitment to the organisation. The importance o... see more
Ali Khodadadizadeh, Katayoun Jahangiri, Davoud Khorasani-Zavareh, Reza Vazirinejad (Author)
BACKGROUND: Vehicle fires are one of the most important causes of fatalities in road traffic injuries (RTIs), but there are no accurate statistics about vehicle fire fatalities (VFFs) due to RTIs in Iran. AIM: This study aimed to investigate the Epidemiol... see more
Shahd Omar AlShamlan, Mutaz Mohammad, Dimitrios Papandreou (Author)
BACKGROUND: Oral health reflects the overall health of an individual; it impacts the mental and physical well-being, quality of life, and social relations of an individual. Special Olympics (SO) athletes have been found to have poorer oral health, and hig... see more
Kiril Mitev, Vaso Taleski (Author)
BACKGROUND: People co-evolved with members of the microbiota and developed, used and adapted many complex immune mechanisms, which are used for monitoring and control of the microbiota. The gut microbiota in cooperation with humans became its essential pa... see more