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Volume 54 Number 1 Year 2018

13 articles in this issue 

Ladyna Rumapar,Sjahjenny Mustokoweni,Alphania Rahniayu

Colorectal carcinoma has high morbidity and mortality rate worldwide, in which over 90% are adenocarcinoma. Colorectal carcinoma is one of the most cancer that metastasize to the lymph node. Angiogenesis have an important role in tumor growth and metastas... see more

Pags. 1 - 5  

Arif Satria Hardika,Dyah Fauziah

Mammary Serine Protease Inhibitor (maspin) is a tumor suppressor gene, a member of the serine protease inhibitor (serpin) family that works by inhibiting motility of cell movement, invasion and metastasis. Maspin expression is expected to be a prognostic ... see more

Pags. 6 - 9  

Silvia Sutandhio,Budiono Budiono,Hardiono Hardiono,Kuntaman Kuntaman,Eddy Bagus Wasito,Maria Inge Lusida

Carbapenemase-producing Escherichia coli (E. coli) has caused trouble in therapeutic antibiotic selection. Carbapenemase screening procedure in laboratories is usually based on inacurate semi-automatic system. Confirmation and classification of carbapenem... see more

Pags. 10 - 15  

Wiwik Werdiningsih,Suhartati Suhartati

Red dragon fruit (Hylocereus polyrhizus) peel contains anthocyanin, fiber and vitamin C, so it can be used to improve lipid profile in dyslipidemia. The peel of the dragon fruit is not durable, so in this study we used freeze-dried dragon fruit peel. The ... see more

Pags. 16 - 21  

Dewi Klarita Furtuna,Kartuti Debora,Eddy Bagus Warsito

Biofilm on medical devices can cause significant diseases and deaths and give a large effecton disease transmission among patients and health providers and potentially increasethe cost of patient treatment. By knowing the presence of biofilm on a patient,... see more

Pags. 22 - 28  

Andri Kustono,I Ketut Sudiana,Fikri Rizaldi,Tarmono Tarmono

The aim of this study was to prove the effects of dexamethasone on immune responses in rats with testicular torsion. This was an experimental study with post test only control group design. In this study, 27 rats were randomly divided into 3 groups. In no... see more

Pags. 29 - 33  

Nyna Puspa Ningrum,Hermanto Tri Joewono,Widjiati Widjiati

Folic acid contains 5-methyltetrahydrofolate (5-MTHF), one of antioxidants that can be used to inhibit reaction caused by cigarette smoke exposure. Folic acid is able to inhibit the levels of Reactive Oxygen Species (ROS) so as to reduce the occurrence of... see more

Pags. 34 - 40  

Alfiah Hayati,Dwi Winarni,Ni Wayan Sukma Antari,Inne Ninda Resita,Erlyn Nurul Fauziah

This study aimed to determine the effects of arak bali on the fragmentation of spermatozoa and testosterone in rats (Rattus norvegicus). This study used 24 rats (170-200 g), divided into four groups: one control and three treatments (receiving arak bali c... see more

Pags. 41 - 45  

Teri Wina Herwati,Yulistiani Yulistiani,Eddy Zarkaty M

Methyldopa is the first-line drugs to treat hypertension in pregnancy. It can decrease blood pressure in preeclampsia by affecting a2-adrenoreceptors in central nervous system. However, it could also act by decreasing  production of sFlt-1 antiangiog... see more

Pags. 46 - 52  

Nur Hadiyanti,Didik Hasmono,Mohammad Saiful Islam

Endothelial dysfunction and vascular injuries are the early processes in thrombogenesis leading to thrombotic stroke. These processes trigger platelet activation characterized by synthesis of Thromboxane A2, potent agonist in platelet aggregation. Acetosa... see more

Pags. 53 - 58  

Adinugraha Amarullah,Didik Hasmono,IGD Ugrasena,Yulistiani Yulistiani

Prednisone has an important role in the therapy of patient with standard risk ALL. Patients with standard risk ALL receiving high dose prednisone as therapy and supraphysiology dose of prednisone are expected to cause suppression in HPA-axis (Hypothalamic... see more

Pags. 59 - 63  

Anang Endaryanto,Mira Irmawati

It is expected that probiotics may act synergistically to improve the clinical efficacy of sublingual immunotherapy (SLIT). The aim of this study was to investigate the role of probiotics in enhancing efficacy of sublingual immunotherapy in childhood alle... see more

Pags. 64 - 74  

Fajar Perdhana,Herdono Purnomo

Right ventricular dysfunction and failure receive much less attention than the left ventricular failure. Right ventricular dysfunction or failure is associated with increased mortality rates in cardiac surgery, surgical cases other than cardiac surgery an... see more

Pags. 75 - 83