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19.875  Articles
1 of 1.989 pages  |  10  records  |  more records»
The publicly available enhanced data of ligands and decoys for estrogen receptor alpha (ERa) which were recently published has made the retrospective validation of a structure-based virtual screening (SBVS) protocol to identify ligands for ERa possible. I... see more

A cyclooxygenase-2 (COX-2) inhibitor celecoxib has been previously reported to have cytotoxic activities towards gastric, prostate, ovarian, colon and breast cancer cell lines. This article reports that the cytotoxic activities of celecoxib could be resul... see more

Lipid nanoparticles, one of nanoparticle technology results has been developed both as a drug delivery system and as a research object. Complex lipid nanoparticle, in the drug delivery system development, has an advantage due to its less toxicity. It is i... see more

One of well-established biological activities for chalcone derivatives is as acetylcholinesterase inhibitors, which can be developed for the therapy of Alzheimer’s disease. Assisted byretrospectively validated structure-based virtual screening (SBVS) prot... see more

Abstract: Rapid and simple quantitative analysis isoflavones tempe using densitometric TLC has been done. The mobile phase of the system was chloroform: methanol: ethylacetate (45: 5: 0.75). Thin layer chromatography was performed on aluminium T... see more

Abstract. The research of identification about sea snake in Tuan Island Waters in Peukan Bada, Aceh Besar District has been conducted. This study aims to determine sea snakes species in Tuan Island Waters. The research was begun from April until July 2018... see more

Mutations in Plasmodium falciparum dihydrofolate reductase (PfDHFR), together with other mutations, hinder malaria elimination in Southeast Asia due to multiple drug resistance. In this article, molecular docking-guided three-dimensional (3D) quantitative... see more

AbstrakZeolit  Lynde Type-A  (LTA)  merupakan zeolit yang tergolong dalam kadar Si/Al rendah. Zeolit LTA memiliki  berbagai  kegunaan,  antara lain  sebagai adsorben, katalis, membran, penukar ion, maupun molecular sieve... see more

Employing ensemble Protein-Ligand Interaction Fingerprints (ensPLIF) as descriptors in post retrospective Structure-Based Virtual Screening (SBVS) campaigns Quantitative Structure-Activity Relationship (QSAR) analysis has been proven to significantly incr... see more

1 of 1.989 pages  |  10  records  |  more records»