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20  Articles
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Drug-induced thrombocytopenia is a common entity in clinical practice. However, having in consideration the severity of the case, it becomes imperative to distinguish non-immune thrombocytopenia from the po-tentially life-threatening immune-mediated ... see more

Introduction: Fenofibrate exerts pleiotropic effects on endothelial cells (ECs) by, amongst others, increasing nitric oxide (NO) production. We aimed to investigate fenofi brate’s putative beneficial actions in healthy or TNF-alpha-induced dysfunctional E... see more

Multienzyme 2-oxoglutarate complex (2-OGDH) together with branched chain ?-ketoacid dehydrogenase (BCKDH) and pyruvate dehydrogenase  belong to the family of mitochondrial 2-oxoacid dehydrogenases. Hypolipidemic drugs, bezafibrate and fenofibrate, up... see more

This study aimed to compare the effects of simvastatin, rosuvastatin, and fenofibrate therapies on the body weight and lipid profiles of the female rats receiving a combination of oral contraceptives (COC) and a high-fat diet (HFD). Twenty female Wistar r... see more

This study aimed to compare the effects of simvastatin, rosuvastatin, and fenofibrate therapies on the body weight and lipid profiles of the female rats receiving a combination of oral contraceptives (COC) and a high-fat diet (HFD). Twenty female Wistar r... see more

The bioanalytical method validation of fenofibrate was performed with all the basic parameter by HPLC using human plasma. This research paper describes a specific procedure for validation of Fenofibrate in human plasma. The mobile phase used was simple an... see more

Purpose: The therapeutic equivalence of multiple registered fenofibrate formulations, several of which are suprabioavailable and therefore marketed at lower dosage strengths than their reference products, is based on the results of bioequivalence studies.... see more

Post-natal overfeeding leads to development of obesity and metabolic dysfunction. PPARaactivation improves steatosis and metabolic dysfunction associated with obesity. Thus, wehave hypothesized that PPARa would prevent the metabolic disorders and obesity ... see more

The most common causative factor in patients with type 2 diabetes is insulin resistance. Achyranthes Aspera Linn. is known as a medicinal plant which has been shown based on previous research to reduce total cholesterol, triglyceride, and blood glucose le... see more

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