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Post-Translational Modification of Human Histone by Wide Tolerance of Acetylation

Cuiling Li, Han-Pil Choi, Xiaoyue Wang, Fei Wu, Xinjun Chen, Xin Lü, Ruirui Jing, Hoon Ryu, Xingyuan Wang, Kazem M. Azadzoi and Jing-Hua Yang

Histone acetylation adds an acetyl group on the lysine residue commonly found within the N-terminal tail protruding from the histone core of the nucleosome, and is important for chromosome structure and function in gene transcription and chromatin remodel... see more

post-translational modifications | mass spectrometry | human histones | acetylation | proteomics

Cells , 2017

Free Access

Unraveling Molecular Differences of Gastric Cancer by Label-Free Quantitative Proteomics Analysis

Peng Dai, Qin Wang, Weihua Wang, Ruirui Jing, Wei Wang, Fengqin Wang, Kazem M. Azadzoi, Jing-Hua Yang and Zhen Yan

Gastric cancer (GC) has significant morbidity and mortality worldwide and especially in China. Its molecular pathogenesis has not been thoroughly elaborated. The acknowledged biomarkers for diagnosis, prognosis, recurrence monitoring and treatment are lac... see more

gastric cancer | LC-MS/MS | Label-free quantitative proteomics | heterogeneous nuclear ribonucleoprotein | Y-box binding protein 1

International Journal of Molecular Sciences , 2016

Free Access

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