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154  Articles
1 of 16 pages  |  10  records  |  more records»
Glioblastoma Multiforme (GBM) is a highly aggressive brain tumor originating from glial cells that is a subset of higher-grade gliomas (HGG). Given the extreme malignancy of GBM and HGG, radiotherapy is often used to shrink tumor and inhibit tumor cell fu... see more

Objective: To report a glioblastoma (GBM) case preceded by a hemorrhagic stroke.Methods: This case reported a 53-year-old male presenting at at Murni Teguh Memorial Hospital, Medan, Indonesia, with a chief complaint of an altered mental state. The conditi... see more

The methylation status of the MGMT promoter represents the valuable prognostic and predictive marker in glioblastoma patients undergoing treatment with alkylating agents such as Temozolomide (TMZ). Although Formalin-Fixed and Paraffin-Embedded Tissue (FFP... see more

Objective. The aim of this study was to establish an optimised protocol for glioblastoma (GBM) cell isolation from brain resection samples, with a high yield and low risk for contamination.Methods. Human GBM cells can be obtained following cranial tumour ... see more

Paper description:Glioblastoma is one of the most fatal and aggressive cancers with unmet clinical needs. Studies in various cell models reported that allicin induces proapoptotic anticancer effects, albeit the mechanism remains unclear.The current study ... see more

Glioblastoma multiforme is the most common and highly aggressive brain tumor, causing high number of death worldwide. Current therapies are not sufficient for patients. The surgical removal followed by radio- and chemotherapy became golden standard. Overa... see more

Glioblastoma multiforme is the most malignant form of central nervous system astrocytoma. The overall survival median in patients with glioblastoma is 12 to 16 months after undergoing resection surgery, chemo radiotherapy and adjuvant treatment; However, ... see more

Glioblastomas são as neoplasias de maior malignidade entre os tumores astrocíticos. O seu prognóstico é ominoso, com poucos anos de sobrevida. Por tratar-se de uma doença tão agressiva, cujo tratamento ainda é bastante limitado, este estudo teve como obje... see more

Thalamic glioblastoma multiforme (GBM) is a rare malignant primary central nervous system (CNS) tumor. Here we report a case of adult unilateral GBM involving the right thalamus. The diagnosis of GBM was first indicated by a region of irregular enhancemen... see more

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