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118.172  Articles
1 of 11.818 pages  |  10  records  |  more records»
Objective: To investigate the relationship between isocitrate dehydrogenase (IDH) 1/2 mutation, telomerase reverse transcriptase (TERT) gene promoter mutation and the prognosis of human glioma patients.Methods: One hundred fifteen patients with human glio... see more

The present study was performed to investigate the effect of 2-fluorobenzaldehyde retinoic acid conjugate on activation of STAT3 pathway in human glioma cells. The results revealed that the compound exhibited inhibitory effect on the activation of STAT3 i... see more

Cancer protective effect of cruciferous vegetables is partly attributed to organic isothiocyanates (ITC) with an N = C = S functional group. Elucidation of the mechanism by which ITCs impart protection against cancer has been the topic of intense research... see more

Resveratrol (RSV) is found in most human foods especially fruits such as grapes, peanuts, strawberry, blueberry, cranberry, mulberry, lingberry, sparkleberry, bilberry and in flowers as well as leaves like butterfly orchid tree, eucalyptus, spruce, lily, ... see more

There is growing evidence that dipeptidyl peptidase IV [DPP-IV, EC 3.4.14.5] takes part in the metabolism of biologically active peptides participating in the regulation of growth and transformation of glial cells. However, the knowledge on the DPP-IV exp... see more

Wild-type p53 (wtp53) is described as a tumour suppressor gene, and mutations in p53 occur in many human cancers. Indeed, in high-grade malignant glioma, numerous molecular genetics studies have established central roles of RTK-PI3K-PTEN and ARF-MDM2-p53 ... see more

Background: Glioblastoma multiforme (GBM) is a primary malignant brain tumor which has poor prognosis. High incidence of oxidative stress-based therapy resistance could be related to the high antioxidant status of GBM cells. Our previous study has reporte... see more

Nimotuzumab is a humanized monoclonal antibody (mAb), a potential anticancer against epidermal growth factor receptor (EGFR)overexpressed by glioma, head and neck, lung, ovarium, and colon cancers. The combination of its use with both external and interna... see more

Human epidermal receptor (HER-1) merupakan anggota famili epidermal growth factor receptor (EGFR) yang banyak diekspresikan glioma. Interaksi HER-1 dengan antibodi monoklonal (Mab) merupakan salah satu pendekatan untuk diagnosis dikaitkan dengan kesp... see more

1 of 11.818 pages  |  10  records  |  more records»