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1.582.029  Articles
1 of 158.204 pages  |  10  records  |  more records»
The aim of the study was to evaluate the effectiveness of ribonucleic acid in the correction of immune disorders in patients with infectious mononucleosis (IM) caused by EBV.Materials and methods. We examined 110 patients with a mean age of 23.3±4.2 years... see more

Abstract. The study of the role of Epstein-Barr virus infection in the development of various human pathological conditions is of great importance. This is due to the significant epidemiological role and social significance, because according to epidemiol... see more

Aproximación a la dinámica de la respuesta inmune en la infección por la COVID-19 / Approach to the dynamics of the immune response in the COVID-19 infection Aproximación a la dinámica de la respuesta inmune en la infección por la COVID-19 / Approach to the dynamics of the immune response in the COVID-19 infectionObjetivo: caracterizar las particularidades de la dinámica de larespuesta inmune durante la infección por la COVID-19.Desarrollo: el sistema inmune juega un papel en la patogeniade la COVID-19 en el que el infiltrado de neutrófilos es un eventoimportante durante la enfermedad. La producción de citocinasproinflamatorias por activaciones anómalas de las vías deseñalización y desregulación en los interferones, son mecanismosinvolucrados en la respuesta inmune de esta enfermedad. Estasevidencias justifican el uso de tratamientos inmunosupresorescomo la metilprednisolona en los pacientes con cuadros graves. Larespuesta inmune adaptativa aparece después de las dos semanasde infección, aunque la IgM se detecta desde la primera semana.La respuesta de los linfocitos T es indispensable en la completaeliminación de la infección viral.Conclusiones: el sistema inmune juega un papel importanteen la destrucción del epitelio alveolar y el desarrollo de lossíntomas graves de la COVID-19, de ahí que los tratamientosinmunomoduladores pueden beneficiar a estos pacientes.Palabras clave: COVID-19; coronavirus; respuesta inmune;inmunopatogenia.ABSTRACTObjetivo: to characterize the peculiarities of the dynamics of theimmune response during infection with COVID-19.Development: the immune system plays a role in the pathogenesisof COVID-19, where the neutrophil infiltrate is an important eventduring the disease. The production of proinflammatory cytokinesby abnormal activations of the signaling and dysregulationpathways in interferons are mechanisms involved in the immuneresponse of this disease. These evidences justify the use of immunosuppressive treatments such as methylprednisolone inpatients with severe symptoms. The adaptive immune responseappears after two weeks of infection, although IgM is detectedfrom the first week. The response of T lymphocytes is essential inthe complete elimination of the viral infection.Conclusions: the immune system plays an important role inthe destruction of the alveolar epithelium and the developmentof severe symptoms of COVID-19, hence immunomodulatorytreatments can benefit these patients.Keywords: COVID-19; coronavirus; immune response;immunopathogenesis.

respuesta inmune durante la infección por la COVID-19.Desarrollo: el sistema inmune juega un papel en la patogeniade la COVID-19 en el que el infiltrado de neutrófilos es un eventoimportante durante la enfermedad. La producción de citocinasproinflamatoria... see more

Objectives: To investigate the changes in the expression levels of peripheral blood immunoregulatory T lymphocytes in children with bronchial asthma accompanied by recurrent infection.Methods: Eighty children with bronchial asthma admitted to the Third Ou... see more

Okra (Abelmoschus esculentus) is reported to have various biological functions such as antioxidant, anticancer and anti-inflammation. However, only few studies have been reported immunomodulatory activities of okra to prevent disease caused by bacteria in... see more

BACKGROUND: The spread of phytocomplex application and justification of its selective effects on tumour cells (mainly due to the presence of flavonoids) require research of its cytotoxic and immunomodulatory activity.AIM: The goal was to study the direct ... see more

Introduction: The main role of probiotics is to maintain homeostasis in the intestines and improve bowel protective function. The aim of the present study is to investigate immuno-modulatory effects of a probiotic consortium.Methods: Observations were car... see more

Antibiotics of the fluoroquinolone series are highly effective synthetic drugs of a wide range of antimicrobial activity. They have a specific mechanism of action on bacterial cells to inhibit the DNA-gyrase enzyme of mostly gram-negative and the topoisom... see more

Background and objective: To our knowledge, no previous studies have focused on the immunomodulatory effects of fresh royal jelly (RJ) administration on systemic lupus erythematosus (SLE) in humans. Our aim was to study the effect of fresh RJ administrati... see more

1 of 158.204 pages  |  10  records  |  more records»