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27.085  Articles
1 of 2.709 pages  |  10  records  |  more records»
The renal stem cell niche represents the most important structure of the developing kidney, responsible for nephrogenesis. Recently, some Authors have reported, at ultrastructural level, a previously unknown complexity of the architecture of renal stem ce... see more

The human adrenal glands arise around the 4th week of gestation and during the intrauterine life produce many substances that are responsible for the maintenance of fetal homeostasis and organ maturation. Stem cell niches represent the microenvironment su... see more

Development of a nephron is induced by a reciprocal exchange of morphogenetic proteins between epithelial and mesenchymal cells within the renal stem/progenitor cell niche. For sustaining concentration of diffusing proteins high, it is believed that an in... see more

Metabolomics has provided new insight into the biology that drives the phenotype of stem cells. During the recent years, metabolic circuits of embryonic and neural stem cells (NSCs) have been better elucidated. Many factors contribute to stem cell determi... see more

Stem/progenitor cells in the adult liver are able to differentiate both into hepatocyte and cholangiocyte lineage. The identification and the role of human liver stem/progenitor cells has been a challenge topic in the recent scientific literature. The exi... see more

Early pancreas development, given its complexity, is generally considered as a paradigm for branching morphogenesis and for the development of two organs in one: the Langherans islets, programmed to secrete hormones into the bloodstream, and the exocrine ... see more

The human uterus is a highly dynamic organ with peculiar plasticity and marked reproductive ability, due to the presence of a vast number of multiple stem/progenitor cell types, including endometrial, stromal and vascular progenitor cells. Conflicting res... see more

Maintenance of mesenchymal stem cells (MSCs) requires a tissue-specific microenvironment (i.e., niche), which is poorly represented by the typical plastic substrate used for two-dimensional growth of MSCs in a tissue culture flask. The objective of this s... see more

BACKGROUND: Metastases are simply known as cancers spread to another part of the body, and often be responsible for the severity of cancer prognosis. Somehow, the complex mechanisms of metastases are not fully understood yet.CONTENT: The characteristic of... see more

1 of 2.709 pages  |  10  records  |  more records»