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8.947  Articles
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As part of our endeavor to enhance survival of natural product derived drug candidates and to guide the medicinal chemist to design higher probability space for success in the anti cancer drug development area, we embarked on a detailed study of the prope... see more

During the early phase of drug discovery, it is becoming increasingly important to acquire the full physicochemical profile of molecules. For this purpose, there is a strong interest in developing efficient and cost-effective platforms for fast and reliab... see more

Block Relevance (BR) analysis is a tool to interpret QSPR/PLS models which can provide the information content of any physicochemical determinant used in property-based drug discovery; its application for the characterization of experimental polarity desc... see more
ADME |  hydrogen bonding |  IAM |  QSPR |  PLS |  PSA |  VIP
In this study Ampicillin drug loaded with alginate and nanocellulose film was prepared by solution casting method. Nanocellulose and ampicillin incorporated into alginate to improve both mechanical and swelling property. The formulated ampicillin loaded A... see more

Evaluation on the physicochemical property of “tempe-dumbo” sausage made from meat of Clarias gariepinus and tempeh flour has been carried out. Randomized design with tree replications were used. Sausages were prepared from tempeh flour and fish meat in t... see more

Purpose: To evaluate the physicochemical properties of the epoxy-resin based root canal cement Sealer 26®, enhanced with different amounts of iodoform. Methods: The properties of setting time, radiopacity, flow, solubility and dimensional stability were m... see more

The oil extracted from Amygdalus pedunculatus (A. pedunculatus) seeds is rich in nutrients. The method of oil extraction is very crucial for preserving its nutrients. The objective of the present study was to compare A. pedunculatus seed oil (APO) samples... see more

Once pesticides reach the soil, there are several factors that affect their soil behavior. To identify the principal soil and herbicide properties that control their adsorption and leaching, a study of five Chilean agricultural and forest soils was perfor... see more

The present study attempted to evaluate the suitable conditions for essential oil extraction from the fruit of Triphasia trifolia using hydrodistillation technique. The effect of various factors such as material size, solvent to solid ratio, heating tempe... see more

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