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7.105  Articles
1 of 711 pages  |  10  records  |  more records»
Objectives: To investigate the prognostic significant of lymph node ratio and surgical margins in patients with colon cancer undergoing surgery.Methods: This observational and retrospective study was conducted at Karadeniz Technical University Medical Fac... see more

BACKGROUND: The American Joint Committee on Cancer (AJCC’s) skin melanoma surgical treatment recommendations from 2011 are characterised by a prima facie "freedom of choice" regarding how extensive should be the excisions for melanomas with tumour thickne... see more

Background: Pelvic bone sarcomas are extremely rare malignant tumours. Patients require a multidisciplinary approach to plan the treatment and complex surgical resections and limb-sparing reconstructions associated with complications, revisions, and funct... see more

Introduction: Ledderhose's disease (plantar fibromatosis) is an uncommon condition that usually affecting men older than 40 years of age and causes major discomfort and disability. The low response to conservative treatment and the progression of surgical... see more

Medication-Related Osteonecrosis of the Jaw (MRONJ) therapy remains an unresolved problem. The proposed conservative and surgical treatment regimens are associated to contradictory success rates. Surgical approach with Er:YAG laser is associated to signif... see more

One step melanoma surgery is, in fact, an innovative combined method for diagnosis and treatment of cutaneous melanoma (at the same time). The methodology allows an accurate assessment of the actual status of the affected patients by 1) clinical status, d... see more

AbstractBackground: The radioguided occult lesion localisation (ROLL) technique was introduced at Groote Schuur Hospital in 2003 replacing the wire-guided localisation (WGL) technique. In the case of preoperative histologically proven impalpable brea... see more

Objectives: In this study, we investigated the expression of zinc alpha-2 glycoprotein in oral squamous cell carcinoma tissue samples. Additionally, ascertained its association to the oral cancer stage and subscale parameters (TNM).Methods: This observati... see more

Dermatofibrosarcoma Protuberans: Presentación De Caso Dermatofibrosarcoma Protuberans: Presentación De CasoIntroducción: El dermatofibrosarcoma protuberans es un sarcoma maligno de tejidos blandos poco frecuente. Representa menos del 0,1 % de todas las neoplasias malignas y menos del 1 % de todos los sarcomas de tejidos blandos, con sus múltiples variantes histológicas.Objetivo: Enfatizar en las opciones terapéuticas y reconstructivas disponibles. Método: Se presenta paciente de 59 años de edad con lesión tumoral en región frontal de 11 años de evolución, con 6 reintervenciones quirúrgicas por varias recidivas, ingresa con reporte de patología benigna, resecada con márgenes amplios de seguridad y cierre con colgajo de avance lateral e injerto de piel total complementario. La biopsia de la pieza quirúrgica demostró la existencia de dermatofibrosarcoma protuberante. Discusión: Ante la sospecha de una lesión maligna se deben tener en cuenta los márgenes de seguridad que en este caso oscilan entre 1 a 5 cm. Las cirugías más seguras son la escisión local amplia con márgenes libres de tumor y cirugía micrográfica de Mohs. El cierre de la zona expuesta será decidido de acuerdo a la edad, localización y disponibilidad de técnicas. Cuando existen dudas de resección incompleta de la lesión se prefiere el uso de injerto autólogo de piel.Conclusiones: Este tumor maligno, aunque infrecuente, puede presentarse en los pacientes de cirugía plástica que buscan su cura con la menor secuela deformante posible. Corresponde al cirujano reconstructivo tener conocimiento de esta entidad y sus opciones terapéuticas, para ofrecer el mejor resultado estético con el menor índice de recidiva.Introduction: Dermatofibrosarcoma protuberans is a rare malignant soft tissue sarcoma. It represents less than 0.1% of all malignant neoplasms and less than 1% of all soft tissue sarcomas, with its multiple histological variants.Objective: to emphasize the therapeutic and reconstructive options available. Method: We present a 59-year-old patient with a tumor lesion in the frontal region of 11 years of evolution, with 6 reoperations due to several recurrences, admitted with a report of benign pathology, resected with wide safety margins and closure with lateral advancement flap and complementary total skin graft. The biopsy of the surgical specimen demonstrated the existence of protuberant dermatofibrosarcoma. Discussion: When a malignant lesion is suspected, the safety margins must be taken into account, which in this case range from 1 to 5 cm. The safest surgeries are wide local excision with tumor-free margins and Mohs micrographic surgery. The closure of the exposed area will be decided according to age, location and availability of techniques. When there are doubts about incomplete resection of the lesion, the use of an autologous skin graft is preferred.Conclusions: this malignant tumor, although infrequent, can occur in plastic surgery patients who seek its cure with the least possible deforming sequela. It is the responsibility of the reconstructive surgeon to have knowledge of this entity and its therapeutic options, to offer the best aesthetic result with the lowest rate of recurrence.


1 of 711 pages  |  10  records  |  more records»