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140  Articles
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Inaccurate diagnoses contributes to the high mortality rate of breast cancer. Human epidermal growth factor receptor 2 (HER2) is overexpressed in breast cancer tumors at around 20–30%. This study aims to develop an electrochemical biosensor for HER2 based... see more

HER2-positive breast cancer is an aggressive form of the disease that is associated with poor prognosis and chemo-resistance. As such, investigation continues into the development of a new HER2-targeted drug for breast cancer. This study investigated the ... see more

Introdução: O câncer de mama é a segunda causa de morte por câncer em mulheres, e 25% dos cânceres de mama expressam o receptor 2 para o fator de crescimento epidérmico (HER2), que confere um comportamento agressivo e prognóstico reservado. Objetivo: Aval... see more

Breast cancer (BC) is the first among all oncological diseases in women and is one of the main causes of female mortality worldwide, including in Ukraine. The HER2 + subtype of breast cancer is characterized by the most unfavorable prognosis. The targeted... see more

Ovarian neoplasms are group of aggressive and lethal diseases.  Surgical and radiochemical therapies on ovarian neoplasm are conventional approaches but with limited progress in years.  Targeted therapy with drugs targeting specific genetic alte... see more

Curcumin as an active ingredient of turmeric acts as repressor against proteins expressed in cancerous cell. However, due to poor absorption, little is known about the effect of curcumin on HER2 expression in blood. A blood samples were drawn from ten sub... see more

BACKGROUND: The rapidly growing knowledge regarding factors controlling tumour growth, with the new modalities of therapy acting on the biological activity of the tumours draw the attention of most cancer researches nowadays and represent a major focus fo... see more

BACKGROUND: HER2 protein expression in gastric carcinoma, in correlation with existing, acknowledged prognostic factors which include the parameters that determine the TNM stage of the disease, could become the basis for ongoing research in the field of m... see more

BACKGROUND: In patients with breast cancer, HER2 gene expression is of a great importance in reacting to Herceptin treatment. To evaluate this event, immunohistochemistry (IHC) has been done routinely on the basis of scoring it and so the patients were di... see more

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