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23  Articles
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BACKGROUND: Non-melanoma skin cancer (NMSC) is the most common malignancy in humans. Targeted therapy with monoclonal antibody cetuximab is an option in case of advanced tumor or metastasis.AIM: We present and update of the use of cetuximab in NMSC search... see more

Cutaneous squamous cell carcinomas (SCC) affecting the regions of the head and neck can be challenging to resect surgically and refractory to chemotherapy or radiation therapy. Consequently; the treatment of squamous cell carcinomas of the skin is a focus... see more


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Periocular malignancies represent between 5% and 10% of all types of skin cancers. The incidence of eyelid (but also the periocular located) malignancies seems to differ in distribution across the continents.  The incidence of eyelid tumours (but als... see more

Targeting of aVß3 and aVß5 integrins by cilengitide may reduce growth of solid tumors including head and neck squamous cell carcinoma (HNSCC). Preclinical investigations suggest increased activity of cilengitide in combination with other treatment modalit... see more

Introducción: Los anticuerpos monoclonales dirigidos al receptor del factor de crecimiento epidérmico (EGFR) han demostrado beneficio clínico en el carcinoma de cabeza y cuello en estadios avanzados, sin embargo, a pesar de los alentadores resultados inic... see more


Purpose: Platinum-refractory or relapsed squamous cell carcinoma of the head and neck (SCCHN) is considered to have poor prognosis. Although cetuximab is currently recommended as category 1 in this group of patients, the use of it is hampered in low- and ... see more

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