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25  Articles
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The aim of the present work was to formulate and evaluate betahistine-loaded chitosan microspheres intended for nasal delivery with focus on their mucoadhesive properties. Betahistine-loaded chitosan microspheres were obtained via W/O emulsion solvent ev... see more

Acyclovir is an antiviral drug, belonging to the deoxyguanosine family, widely prescribed for the treatment of herpes simplex viral infections, as well as in the treatment of herpes zoster (shingles). Oral bioavailability of acyclovir is very low (10–20%)... see more

The main aim of pharmaceutical research is steadily shifted from the development of new chemical entities to the development of novel drug delivery system of existing drug molecule to maximize their effectiveness in terms of therapeutic action, patent pro... see more

The present research is aimed to develop a mucoadhesive drug delivery system exhibiting a unique combination of mucoadhesion and controlled drug release in systemic manner to prolong residence in the soft palatal mucosa using rosiglitazone maleate as a mo... see more

Objetivo: Los parches de mucoadherente bucal fueron desarrollados y evaluados por la administración sistémica de la pioglitazona en la cavidad oral. Pioglitazona pertenece a una clase nueva de medicamentos antidiabéticos orales conocida como tiazolidindio... see more

Chitosan is a cationic polymer derived by deacetylation of chitin obtained from crustaceans. Biodegradable and mucoadhesion properties of chitosan have recently led to increasing the interest. Chitosan can be used as raw material for the manufacture of fi... see more

MODERN STATE OF CREATION, PRODUCTION AND RESEARCH OF DRUGSI.V. Kozak, M.B. Demchuk, T.A. HroshovyiI.HorbachevskyTernopilStateMedicalUniversityIntroduction. Creating new systems and drug delivery aimed at increasing the effectiveness and safety of treatmen... see more

Gelatin is a proteinaceous substance composed of all the essential amino acids (except tryptophan) and derived from collagen using a hydrolysis technique. Hydrogels and modified composites based on gelatin are widely used in the food industry, biomedicine... see more

In the present research work mucoadhesive microspheres of cimetidine was prepared using ionotropic gelation technique. All the microspheres were characterized for particle size, scanning electron microscopy, FT-IR study, DSC, percentage yield, drug entrap... see more

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