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106  Articles
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The aim of work was to make biochemical investigations for detection of pro-oxidant and antioxidant systems markers in guinea pigs` bronchi before and after treatment of thiotriazolin during experimental allergic alveolitis development. Gradual elevation ... see more

Exogenic allergic alveolitis has been ascribed to multiple inhaled antigens found in a large variety of environmental settings. The immune mechanisms leading to this deases development are still incompletely understood. Initially, believed to be a classes... see more

In result of a targeted synthesis, a promising substance for new anticonvulsant drug creation – symmetrical dybenzyl amid of malonic acid – was found.The ability to be synthesized in one stage from available reagents and with high yield, as well as to sho... see more

The aim of the study was to improve the in-vitro dissolution rate of quercetin (Qu) using cocrystallization of quercetin. Cocrystals of quercetin (Co Qu) were produced with malonic acid (Ma) as coformer at ratio 1:2 using solvent evaporation method. Cocry... see more

A highly relevant problem of modern veterinary science is the study of features and mechanisms of combined action of the most common heavy metals – cadmium and plumbum and their influence on the body of humans and animals in the regions of Ukraine under t... see more

The article have been devoted to screening tests hypoglycemic action of 43 new derivatives of malonic and oxalic acids. Studies carried out on rabbits with normal blood glucose. The studied compounds were administered at a dose of 1/20 LD50. Comparison dr... see more

THE EXPERIMENTAL STUDY OF THE ANALGESIC AND ANTIPYRETIC ACTIVITY OF THE NEW MALONIC ACID DERIVATIVES -MALDENN. ?. VakhninaNationalUniversityofPharmacy, Kharkiv      Introduction. The article is devoted to the study of analgesic and ant... see more

The article have been devoted to screening tests hypoglycemic action of 43 new derivatives of malonic and oxalic acids. Studies carried out on rabbits with normal blood glucose. The studied compounds were administered at a dose of 1/20 LD50. Comparison dr... see more

The purpose of this work was to explore the formation of ketoprofen-malonic acid cocrystal by solvent evaporation method. Early detection of cocrystal formation was conducted by hot stage microscopy and solid-liquid phase diagram. Cocrystal were prepared ... see more

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