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54  Articles
1 of 6 pages  |  10  records  |  more records»
Ketoprofen yang beredar di Indonesia sebagian besar dalam bentuk sediaan tablet salut enterik, tetapi metoda analisis untuk penetapan kadar dan uji disolusinya belum tersedia dalam farmakope.  Tujuan dari penelitian ini adalah  mengembangkan met... see more

Tablet salut enterik Ketoprofen adalah obat yang beredar luas di  Indonesia. Digunakan  untuk mengatasi nyeri arthiritis tulang, rematik dan demam. Namun, sejauh ini uji disolusinya secara spesifik belum tersedia dalam farmakope manapun.  U... see more

Nyeri akut pascaoperasi didefinisikan sebagai rasa nyeri yang muncul setelah prosedur pembedahan.  Tujuan penelitian ini adalah membandingkan efek kombinasi ketoprofen supositoria+parasetamol oral dengan meperidin intravena sebagai analgetik pascaope... see more

After oral administration of the drug, drug dissolution is a requirement for absorption of a drug into the systemic circulation. Based on the classification Biopharmaceutical Classification System (BCS), ketoprofen is included in class II, which has low s... see more

The coating stability of ketoprofen by chitosan-guar gum gel has been studied. Into 228.6 mL of 1.75% (w/v) chitosan solution in 1% (v/v) acetic acid, 38.1 mL of guar gum (gg) solution was added with concentration variation of 0.35, 0.55, and 0.75% (w/v) ... see more

Chitosan-alginate membrane diffusion behavior has been investigated for its application in drugs delivery system. Ketoprofen diffusion behavior assay were performed at 37 and 42 °C to membrane thickness (h) and donor cell concentration of ketoprofen varia... see more

Telah dilakukan peningkatan laju disolusi ketoprofen sebagai model zat aktif yang sukar larut air dengan teknik penggilingan bersama (co-grinding) dengan polimer hidrofilk hydroxypropyl methylcellulose E6 (HPMC) menggunakan alat mortar grinder. Tiga formu... see more

Tujuan penelitian ini yaitu formulasi granul mukoadhesif ketoprofen menggunakan polimer kitosan. Granul ketoprofen dibuat dengan metode granulasi basah dengan konsentrasi polimer kitosan 0%, 10%, 20%, dan 30% (b/v). Granul dievaluasi secara fisika dan kim... see more

The purpose of this work was to explore the formation of ketoprofen-malonic acid cocrystal by solvent evaporation method. Early detection of cocrystal formation was conducted by hot stage microscopy and solid-liquid phase diagram. Cocrystal were prepared ... see more

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