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55  Articles
1 of 7 pages  |  10  records  |  more records»
The Present work was to develop a simple, fast, accurate, precise, reproducible, Reverse Phase High Performance Liquid Chromatographic Method for simultaneous estimation of Valsartan and Sacubitril in Pharmaceutical dosage form. Chromatographic separation... see more

Objective: To investigate the effect of valsartan combined with nifedipine controlled-release Tablets on diabetic nephropathy (DN) patients with hypertension.Methods: The clinical records of 80 DN patients with hypertension registered in our hospital from... see more

Neprilysin (NEP) is an enzyme present in several body cells and is involved in the degradation of natriuretic peptides (NPs), bradykinin (BK), and adrenomedullin (ADM). Furthermore, sacubitril/valsartan (LCZ696), the first agent of Angiotensin Receptor Ne... see more

Insulin resistance is a major risk factor for patients with type 2 diabetesmellitus (T2DM). Telmisartan and valsartan are angiotensin II type I receptorblockers (ARBs) that are often used in patients with metabolic syndrome andT2DM. This study aimed to co... see more

The main objective of present work was to prepare a solid SEDDS for enhancement of oral bioavailability of Valsartan, poorly water soluble drug. The solubility of the drug was determined in various vehicles. A pseudo ternary phase diagram was constructed ... see more

The main objective this study is to prepare and evaluate the selfnanoemulsifying drug delivery (SNEDDS) system in order to achieve a better dissolution rate of a poorly water soluble drug valsartan.  The present research work describes a SNEDDS of va... see more

The objective of the present work was to enhance the solubility and dissolution rate of valsartan (VAL) a poorly water soluble antihypertensive, by spherically agglomerated solid dispersions using methanol, water and dichloromethane as good solvent, poor ... see more

Reduction of circulating endothelial progenitor cells (EPCs) are considered as strong and robust biomarkers for prediction of cardiovascular outcomes in both chronic heart failure and diabetic populations. The aim of this study was to assess the effect of... see more

A simple, rapid, precise, accurate and sensitive spectrophotometric method has been developed for the simultaneous estimation and validation of Nebivolol Hydrochloride (NEB) and Valsartan (VAL) in pure and combined tablet dosage forms. Pure drug samples o... see more

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