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11.233  Articles
1 of 1.124 pages  |  10  records  |  more records»
Trastuzumab, a humanized monoclonal antibody against the extracellular domain of human epidermal growth factor receptor 2 (HER-2) prolongs disease-free survival (DFS) and overall survival (OS) in patients with early-stage breast cancer. Although it is gen... see more

Introduction: Endometrial carcinoma is the most common gynaecological neoplasm in developed countries. The disease is mostly asymptomatic at an early stage, however there is no direct marker which could result in detection of cancer earlier. Nowadays the ... see more

Human saliva is a clear, slightly acidic biological fluid containing a mixture of secretions from multiple salivary glands, including the parotid, sublingual gland other minor glands beneath the oral mucosa as well as gingival crevice fluid.  Salivar... see more

In the absence of ischemic changes on ECG should be assessed biomarkers to exclude myocardial infarction (MI), and further diagnostic testing to exclude ischemia in patients without MI. Although for the diagnosis of MI is routinely used by a number of bio... see more

Paper description:Molecular biomarkers of oxidative stress are the most apropriate parameters for detecting early influence of pollutants. The effects of trout farms on aquatic insects at the molecular level have been scantily investigated.We examined the... see more

Recent changes in lung cancer care, including new approvals in first line and the introduction of high-throughput molecular technologies in routine testing led us to question ourselves on how deeper molecular testing may be helpful for the optimal use of ... see more

Tumor-derived extracellular vesicles (TEVs) are membrane-bound, nanosized vesicles released by cancer cells and taken up by cells in the tumor microenvironment to modulate the molecular makeup and behavior of recipient cells. In this report, we summarize ... see more

Chronic Thromboembolic Pulmonary Hypertension (CTEPH) is a debilitating disease, for which the underlying pathophysiological mechanisms have yet to be fully elucidated. Occurrence of a pulmonary embolism (PE) is a major risk factor for the development of ... see more

Embryonal tumors of the central nervous system represent a heterogeneous group of childhood cancers with an unknown pathogenesis; diagnosis, on the basis of histological appearance alone, is controversial and patients’ response to therapy is difficult to ... see more

1 of 1.124 pages  |  10  records  |  more records»