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Formulation Development and in vivo Evaluation of Nevirapine Solid Dispersions by Solvent Evaporation Technique

D.V.R.N Bhikshapathi,Medipalli Viswaja,

The objective of the present investigation is focused on the preparation of solid dispersions containing Nevirapine. The effect of various hydrophilic polymers on the aqueous solubility was studied. Kolliphor P188 was selected as carrier and solid dispers... see more

Nevirapine | Solid dispersions | Kolliphor P188 | HIV | Bioavailability studies.

International Journal of Pharmaceutical Sciences and Drug Research , 2018

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Application of Simplex Lattice Design on the Optimization of Andrographolide Self Nanoemulsifying Drug Delivery System (SNEDDS)

Oktavia Indrati,Ronny Martien,Abdul Rohman,Akhmad Kharis Nugroho

Background: Optimization of self-nanoemulsifying drug delivery system (SNEDDS) formulation is an important step to obtain optimal formulation with desired characteristics.Objective: This present study was aimed to utilize simplex lattice design in optimiz... see more

andrographolide | snedds | simplex lattice design

Indonesian Journal of Pharmacy , 2020

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Enhancement of solubility and oral bioavailability of poorly soluble drug Valsartan by novel solid self emulsifying drug delivery system

B Usha Sri,Y Indira Muzib,D.V.R.N. Bhikshapathi,R Sravani

The main objective of present work was to prepare a solid SEDDS for enhancement of oral bioavailability of Valsartan, poorly water soluble drug. The solubility of the drug was determined in various vehicles. A pseudo ternary phase diagram was constructed ... see more

Valsartan | solid SEDDS | particle size | neusilin US2 enhanced oral bioavailability

International Journal of Drug Delivery , 2015

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