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12.288  Articles
1 of 1.230 pages  |  10  records  |  more records»
Continuing the search for biologically active substances among 2-R-phenyl?m?noth?azole derivatives a new series of N-[4-methyl(41-chlorophenyl)-2-R-phenyl?m?noth?azol-3-yl]-morpholine derivatives has been synthesized by Hantzsch reaction. Hydrochlorides o... see more

Molecular sieve supported lanthanum catalyst proved to be an efficient heterogeneous catalyst for the one-pot, four-component synthesis of polyhydroquinoline derivatives from aromatic aldehydes, dimedone, ethyl acetoacetate and ammonium acetate in ethanol... see more

It is shown that thioacetamide are comfortable synthetic blocks for various heterocycles, including thiazole containing a double exocyclic bonds. This work describes the synthesis of (Z)-2-((Z)-5-arylidene-4-oxo-3-arylthiazolidin-2-ylidene)-N-arylethaneth... see more

The treatment of infectious diseases is one of the global problems of modern medicine. Despite the large amount of medications the problem of creation of new highly effective antimicrobials is a relevant task. This is, mainly, due to the increase of micro... see more

In the view of extensive literature survey which revealed the anticonvulsant profile of 1,4-dihydropyridines and 1,3,4-oxadiazoles, we have coupled these two moieties with the aim of achieving enhanced anticonvulsant effect. The synthesis of novel compoun... see more

This review covers the literature published over the last 5 years on the practical use, synthesis, and oxidation of 1,4-dihydropyridines (1,4-DHP). A summary is given on recent research on the biological activity of 1,4-DHP (Hantzsch esters) as antioxidan... see more

Years after the first report on 1,4-dihydropyridines (1,4-DHPs) and 1,2,3,4-tetrahydropyrimidines (1,2,3,4-THPMs) appeared, they  are revisited as plausible therapeutic agents. This is mainly due to the convenient methods that exist for their synthesis an... see more

DOI: 10.1590/2179-8966/2022/60100AbstractIn this theoretical essay, we shed light on new forms of public stigmatisation and their possible outcomes for the criminal justice system. We present some examples of the phenomenon we name “cancelling crusade” in... see more

Abstract - The oxidation of L-Tyrosine by molecular iodine was studied using semi-empirical and density functional theory methods. Molecular information such as net charges, values of frontier orbital energies, composition, proportions and bonding contrib... see more

1 of 1.230 pages  |  10  records  |  more records»