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409  Articles
1 of 42 pages  |  10  records  |  more records»
Diabetes Mellitus (DM) was a disease characterized by the occurrence of hyperglycemia. This study aimed to analyze the activity of compounds in traditional medicinal plants as potential anti-diabetic candidates using the MM method and to analyze the inter... see more

Searching for effective and safe aldose reductase (AR) inhibitor agent is a major thrust area in the mainstream of anti-cataractogenic research. This study was set up to investigate the in vitro aldose reductase inhibitory (ARI) activity of fractions of m... see more

Aldose reductase (AR) enzyme and advanced glycation endproducts (AGEs) play an important role in diabetic complications such as cataracts. The purpose of this study was to look into two standardized plant extracts used in Ayurvedic medicine for the treatm... see more

A novel class of ferulic acid derivatives with urea groups were synthesized and evaluated for hypoglycemic and aldose reductase inhibition activities. Several compounds showed comparable in vivo hypoglycemic agents to the commercial drug glibenclamide. Fu... see more

The Liver is an important organ of the body for carbohydrate metabolism which include ureogenesis, glycogenolysis, gluconeogenesis. The pituitary hormone vasopressin mediates its actions on the carbohydrate metabolism through the V1 receptors expressed in... see more

Diabetes mellitus (DM) is a metabolic syndrome characterized by hyperglycemia and glucose intolerance, due toinsulin resistance, insulin deficiency, or both. Diabetics retinopathy (DR) is a DM complication due to retinal abnormality,that causes vision red... see more


Background: Sorbitol, also less commonly known as glucitol, is a sugar alcohol with a sweet taste metabolizesdslowly in human body. It is also called the sorbitol-aldose reductase pathway, the polyol pathway appears to be implicated in diabetic complicati... see more

 The marketing research of antidiabetic drugs presented at the pharmaceutical market of Ukraine has been conducted. The product range of the group of antidiabetic drugs has been studied according to the ATC classification, manufacturing countries and... see more

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