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3.491  Articles
1 of 350 pages  |  10  records  |  more records»
Colorectal carcinoma (CRC) represents a global health problem. The EGFR signaling pathway is very important in the initiation of different human epithelial cancers and plays a key role in colorectal carcinogenesis. Considering the role of EGFR as a mitoge... see more

The aim of this study was to investigate the expression of cyclooxygenase type-2 (COX-2) and its association with angiogenesis and clinicopathologic characteristics of colorectal carcinoma (CRC). COX-2 expression was detected by means of immunohistochemis... see more

Objective: The loss of expression of syndecansyndecan-1 is associated with poor prognosis in many types of human cancer. The objective of this study was to evaluate the relation between syndecan-1 immunoexpression and several clinicopathological parameter... see more

Objective: To analyze the changes of hemorheology, haemodynamics and immune function of patients during propofol intravenous anesthesia in the radical resection of colorectal carcinoma and its significance.Methods: The study included 112 patients who unde... see more

BACKGROUND: The most widely used tumour markers, especially in colorectal malignancy, is Carcinoembryonic antigen (CEA).AIM: This study was aimed to investigate CEA value among the degree of differentiation and tumour location.METHODS: A cross-sectional a... see more

BACKGROUND: Microsatellite instability (MSI) is the genetic pathway underlying 15% of sporadic colorectal carcinoma (CRC) and hereditary non-polyposis CRC. MSI-H CRC has a distinct clinicopathological characteristic including excess mucin and signet ring ... see more

BACKGROUND: Growing evidence supports the notion that the onset of tumorigenesis could occur through cancer stem cells (CSCs). These tumour cells show low proliferative rates, high self-renewal capacity, propensity to differentiate into active proliferati... see more

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