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95  Articles
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The aim of the present investigation was to development of immediate release liquid coated pellets of poorly soluble drugs Amlodipine besylate (AMD) and Nebivolol HCl (NBV) by novel liquid layering technology to enhance solubility and bioavailability with... see more

Topicality. Amlodipine besylate belongs to the group of calcium channel blockers, derivative from 1,4-dihydropyridine. The pharmacological effects of amlodipine are the cause its effectiveness in the treatment of hypertension and the vasospastic form of s... see more

Topicality. Amlodipine besylate belongs to the group of calcium channel blockers, derivative from 1,4-dihydropyridine. The pharmacological effects of amlodipine are the cause its effectiveness in the treatment of hypertension and the vasospastic form of s... see more

Background:Amlodipine is a Ca++ channel blocker, routinely used for treatment of hypertension. The mechanism underlying its anti-hypertensive effect is dilatation of blood vessels. Testosterone, the hormone produced by testis, is responsible for developme... see more

The study is based on the determination of amlodipine besylate (AB) after derivatization with 4-dimethylaminobenzaldehyde (DMAB) using UV/Visible spectrophotometer at pH 5 to yield derivative that is measured at ? max 399 nm. The calibration graph obtaine... see more

Creation of drugs for treating hypertension, namely the combined tablets based on antihypertensive agents of different pharmacological groups, is very important for domestic pharmaceutical science and practice. According to the results of the previous stu... see more

Creation of drugs for treating hypertension, namely the combined tablets based on antihypertensive agents of different pharmacological groups, is very important for domestic pharmaceutical science and practice. According to the results of the previous stu... see more


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