Journal title
Cancers

   

 Articles related

Nathalie BEAUJEAN    

In mammals, epigenetic markers are globally rearranged after fertilization: while gametes carry special epigenetic signatures and a unique nuclear organization, they attain embryo-specific patterns after fertilization. This “reprogramming” is promoted by... see more


Panagiotis Douvaras, Tomasz Rusielewicz, Kwi Hye Kim, Jeffery D. Haines, Patrizia Casaccia and Valentina Fossati    

Pluripotent stem cells provide an invaluable tool for generating human, disease-relevant cells. Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system, characterized by myelin damage. Oligodendrocytes are the myelinatin... see more


Ramón Cacabelos and Clara Torrellas    

Epigenetic variability (DNA methylation/demethylation, histone modifications, microRNA regulation) is common in physiological and pathological conditions. Epigenetic alterations are present in different tissues along the aging process and in neurodegener... see more


Brittany R. Silverman and Jiaqi Shi    

Pancreatic cancer is one of the most aggressive human cancer types with a five-year survival less than 7%. Emerging evidence revealed that many genetic alterations in pancreatic cancer target epigenetic regulators. Some of these mutations are driver muta... see more


Brooke D. Paradise, Whitney Barham and Martín E. Fernandez-Zapico    

Pancreatic cancer has one of the highest mortality rates among all types of cancers. The disease is highly aggressive and typically diagnosed in late stage making it difficult to treat. Currently, the vast majority of therapeutic regimens have only modes... see more

Revista: Cancers