12 articles in this issue
O. O. Kremzer
Reduction of circulating endothelial progenitor cells (EPCs) are considered as strong and robust biomarkers for prediction of cardiovascular outcomes in both chronic heart failure and diabetic populations. The aim of this study was to assess the effect of... see more
O. S. Nalyotova
It has been proven that monotherapy with aliskiren (150-300 mg/day) and nebivolol (5-10 mg/day) provides hypertensive patients of stage II (essential hypertension) with effective decline of office systolic (SP) and diastolic (DP) blood pressure values to ... see more
P. B. Antonenko,V. I. Kresyun
As proven earlier, in patients with tuberculosis (TB) the concentration of antituberculosis drugs like isoniazid and rifampicin may differ depending on polymorphism of CYP2C19. The aim of the research was to determine the peculiarities of the pulmonary TB... see more
S. V. Fedorov
Heart failure (HF) is a consequence of various heart diseases. Approximately 1%-2% of the adult population in developed countries has HF, with the prevalence rising to = 10% among persons of 70 years old or older. Ivabradine is the first member of a new g... see more
O. V. Makarenko,O. V. Kryvoviaz,S. O. Kryvoviaz
The aim of the study was to determine the need in antiglaucoma drugs in non-monetary and monetary terms per a patient for one year of treatment using the ATC/DDD methodology. The theoretical value of monotherapy for one patient per year has been calculate... see more
R. D. Zakrutnyi,S. Yu. Shtrygol’,S. I. Merzlikin
The aim of our study was to determine the effect of diacamph hydrochloride, an original antihyperglycemic drug, on the cortisol content in the blood of animals with a combined model of diabetes mellitus and chronic stress. The experiment was performed on ... see more
I. F. Belenichev,L. I. Kucherenko,Yu. A. Volchik,O. O. Nagorna,I. A. Mazur,N. V. Parnyuk,M. O. Avramenko,O. O. Portna
In spite of achievements in the sphere of highly effective drugs creation for treating cardiovascular diseases the problem is still urgent since mortality is high because of these diseases, and it takes the 2-nd – 3-d place among the population of industr... see more
O. A. Kolisnyk,O. G. Chistyakov,S. M. Drogovoz,A. Yu. Pozdniakova
Improvement of the methods of extraction of biologically active substances from the plant raw material is one of the forms of herbal drugs optimization. When treating gastric ulcer it is expedient to use the complex therapy oriented to neutralization of h... see more
V. I. Grytsenko
The methodology of creating the suppositories for the treatment of prostate diseases has been grounded. Benign prostatic hyperplasia (BPH) and chronic prostatitis are among the most common urologic diseases in men. In recent years, at the pharmaceutical m... see more
O. M. Shapoval,S. Yu. Shtrygol,V. L. Karbovskiy,I. A. Shevchuk,O. V. Kurkina,T. Ye. Makovska
In this work the results of studying the influence of Prosteks® drug, rectal suppositories, produced by “Biopharma”, PJSC on the turpentine prostatitis in rats are presented. The relevance of the work is due to the fact that among the urological diseases ... see more
N. S. Iurchenko,T. V. Ilyina,A. M. Kovalyova,A. O. Klymenko,V. M. Ivanochko
Sweet woodruff (Asperula odorata L.) of Rubiaceae Juss. family is not officinal plant, which is used in folk medicine as a sedative, diuretic and choleretic agent. The hepatoprotective activity of a dry extract of sweet woodruff herb has been determined e... see more
O. F. Piminov,L. I. Shulga,T. S. Beztsenna
The work is devoted to possible approaches concerning the search of promising plant objects for creating new medicines and their use by the example of herbal collections for dental practice. 110 prescriptions of folk and traditional medicine used for the ... see more