11 articles in this issue
Manoj Ashok Wagh,Dilip Parag Kothawade,Kishor Sahebrao Salunkhe,Nayana Vijay Chavan,Vandana Radheshyam Daga
Formulation of a convenient dosage form for administration, by considering swallowing difficulty and poor patient compliance, leads to development of orally disintegrating tablets. This are also called as orodisperse, mouth dissolving, rapidly disintegrat... see more
Mosbah A. El-Majri,Rakesh kumar Sharma
Piroxicam suppositories were prepared by using water soluble and oil soluble suppository bases. All the prepared suppositories were evaluated for various physical parameters like weight variation, drug content and hardness, melting point, disintegration a... see more
Vivek Ranjan Sinha,Vinay Jindal,Saurabh Srivastava,Honey Goel
Oral extended release products offer potential advantages in patient compliance and therapeutic outcomes like sustained blood levels with attenuation of adverse effects. In neuropsychiatric disorders like depression, most of the formulations serve a marke... see more
Dhirendra Kumar,Vivek Dave,Shaila Lewis,Brajesh Parmar,Kavita R. Gajbhiye,Sarvesh Paliwal
The aim of the present study was to formulate once daily sustained release matrix tablets of Stavudine to increase therapeutic efficacy, reduce frequency of administration and improve patient compliance. The sustained release tablets were prepared by dire... see more
Ashok Kumar,Manisha Pandey,M K Koshy,Shubhini A Saraf
Fast swelling highly porous superporous hydrogels (SPH) are synthesized through a method utilizing rapid solution polymerization of acrylic acid for development of gastric retention devices. The swelling property, mechanical strength and release profile o... see more
R. P. Patel,B. Dadhani,R. Ladani,A.H. Baria,Jigar Patel
The present investigation deals with the formulation, optimization and evaluation of sodium alginate based In situ gel of Clarithromycin and Metronidazole Benzoate. Sodium alginate used as a polymer and CaCO3 was used as a cross-linking agent. The In situ... see more
Prashant Khemariya,Sachin Mishra,Amit Shukla,Mohit Bhargava,Sanjay K. Singhai,Sanjay Goswami
The rationale of this research was to prepare a gastroretentive drug delivery system of Ranitidine HCL. Floating Drug delivery system used to target drug release in the stomach or to the upper part of the intestine. The oral delivery of Ranitidine is test... see more
Jitendra Behera,Raj K. Keservani,Arvind Yadav,Meenendra Tripathi,Anoop Chadoker
Methoxsalen has been used for the treatment of psoriasis. In order to develop alternative formulations for the topical administration of methoxsalen, chitosan coated microemulsion were evaluated as delivery vehicle. Microemulsions were prepared using wate... see more
P. Muthuraman,S. Ravikumar,J. Vikramathithan,G Nirmalkumar,K Srikumar
Dietary phytohormones may influence the metabolic processes in animal cells. To determine the effect of the plant growth regulators 28-homobrassinolide, gibberellic acid and kinetin on the tissue hexokinase and some blood components in male rats. Methods:... see more
Hima Bindu TVL,M Vidyavathi,Kavitha K,TP Sastry,Suresh kumar RV
Natural polymers are used as lead compounds for design of drugs in treatment of different ailments. Chitosan and gelatin have proven wound healing properties individually. As both have wound healing property, the combination of these two polymers and inco... see more
Pankaj P. Amrutkar,Sanjay B. Patil,Abhijeet N. Todarwal,Manoj A. Wagh,Parag D. Kothawade,Rajendra K. Surawase
Lamotrigine, an antiepileptic drug (AED) of the phenyltriazine class, is chemically unrelated to existing antiepileptic drugs. Lamotrigine is also used in the treatment of depression and bipolar disorder. But it is a bitter drug and slightly soluble in wa... see more