10 articles in this issue
Muhammad Agus Aulia,Keri Lestari,Ahmad Faried,Cynthia Retna Sartika,Andi Wijaya,Achmad Adam,Hanna Gunawan,Rima Haifa,Nabilla Farah Naura,Billy Yosua Costantin Pongajow
BACKGROUND: Stroke is one of many leading causes of death and disability worldwide. Despite decades of research, treatment for stroke recovery is still inadequate. Recently, mesenchymal stem cell (MSC) therapy is considered as one of the potential treatme... see more
Habibah Faroque,Nur Soleha Aria,Nor Amira Muzilah,Hamid Ali Nagi Al-Jamal,Mohd Fadliyazid Ab. Rahim,Yasuhiro Nakamura,Hironobu Sasano,Abdullah Azmahani
BACKGROUND: The checkpoint kinase 1 (CHEK1) and glutamine-fructose-6-phosphate aminotransferase 1 (GFPT1) genes have been reported to have a crucial role in carcinogenesis in colorectal cancer (CRC). However, their association with the pathogenesis of CRC... see more
Irma Rahayu Latarissa,Melisa Intan Barliana,Anna Meiliana,Ida Paulina Sormin,Erizal Sugiono,Cissy Bana Kartasasmita,Irmansyah Irmansyah,Keri Lestari
BACKGROUND: Before WHO revoked the emergency use authorization for Chloroquine (CQ) and Hydroxychloroquine (HCQ) because of their side effects, it was suggested to use these two drugs for COVID-19 therapy. In addition, another derivate of quinine, namely ... see more
Christiana Tri Nuryana,Tiara Puspita Agustin,Sofia Mubarika Haryana,Yohanes Widodo Wirohadidjojo,Nur Arfian
BACKGROUND: Ultraviolet B (UVB) induces skin photoaging by reducing collagen deposition via impairment of the TGF-ß/Smad signaling pathway. Achatina fulica mucus (AFM) is a native medicine acting as vehicle of anti-aging ingredients. The present investiga... see more
Rina Triana,Indriyanti Rafi Sukmawati,Mas Rizky Anggun Adipurna Syamsunarno,Keri Lestari
BACKGROUND: Type 2 diabetes mellitus (T2DM) is the most common metabolic disorder associated with oxidative stress and chronic inflammation. Understanding the regulatory mechanisms related to the role of nuclear factor erythroid 2 (Nrf2), a master regulat... see more
Bogi Pratomo Wibowo,Handono Kalim,Husnul Khotimah,Hidayat Sujuti,Ettie Rukmigarsari,Nabila Erina Erwan
BACKGROUND: Colorectal cancer (CRC) is reported as the third most frequently diagnosed cancer worldwide. Salmonella infection plays a role in developing this cancer, which is chronically related to the avirulence protein A (AvrA) effector protein produced... see more
Nur Irawati,Heri Wibowo,Ani Retno Prijanti,Rona Kartika,Dicky Levenus Tahapary
BACKGROUND: Cluster of differentiation (CD)36 and adenosine triphosphate-binding cassette transporter A1 (ABCA1) are 2 macrophages-expressed receptors that promote cholesterol uptake and efflux, in which their imbalance might be associated with the foam c... see more
Michael Kevin,Nyoman Suci Widyastiti,Selamat Budijitno,Yan Wisnu Prajoko,Neni Susilaningsih
BACKGROUND: Andrographis paniculata has anti-inflammatory, anti-cancer, and immunomodulatory effects. Intercellular adhesion molecule-1 (ICAM-1) and E-selectin are released in inflammatory conditions due to sepsis. In sepsis-associated fatalities, E-selec... see more
Lina Hadi,Albert Manggading Hutapea,Florenly Florenly
BACKGROUND: Orthodontic tooth movement (OTM) may increase the risk of treatment-related complications for some diabetes mellitus (DM) patients. Hydrogen-rich water (HRW) has been demonstrated in many studies to reduce oxidative stress and cell damage. Thi... see more
Pande Kadek Aditya Prayudi,I Gde Sastra Winata,I Nyoman Gede Budiana,Kade Yudi Saspriyana,I Nyoman Bayu Mahendra,Ketut Suwiyoga
BACKGROUND: The need for clinically useful biomarkers which can predict the surgical outcome after primary debulking surgery (PDS) in patients with advance ovarian cancer (AOC) is really important. Insulin-like growth factor-binding protein 2 (IGFBP2) is ... see more