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4.491  Articles
1 of 450 pages  |  10  records  |  more records»
The aim of the present investigation was to examine and demonstrate in detail the anti-cancer and apoptotic effects of daucosterol in human colon cancer cell line HCT-116. The effects of this compound on cell migration, cell invasion, cell cycle analysis ... see more

Despite advances in conventional therapies, treatment of prostate cancer is still a challenge. The study aims to assess the possible anti-cancer effects of tangeretin, a dietary flavonoid on human prostate cancer cells (DU145, PC3, LNCaP). Tangeretin (25,... see more

Human osteosarcoma is the most prevalent primary malignant bone tumor with high frequency of invasion and metastasis. Strong resistance coupled with toxicity of the currently available chemotherapeutic drugs poses challenge in treatment. The study aimed t... see more

Cadmium, a toxic environmental contaminant, induces oxidative stress leading to various neurodegenerative disorders, where it interferes with homeos-tasis of intracellular free calcium ([Ca2+]i), leading to cellular damage and apoptosis. We investigated w... see more

The objective of the current study was to evaluate the antiproliferative and apoptotic activities of acetoxyroyleanone against various cancer cells along with studying its effect on chromatin condensation, NF-?B and caspase-3 expressions and cell migratio... see more

Yellow ripe banana skin is rich in flavonoid compounds, and contains other phenolic compounds. The presence of flavonoids and other phenolic compounds in banana peels needs to be identified and tested for their activities, so as to increase the utilizatio... see more

The aim of the present study was to evaluate the antitumor and anti-angiogenic effects of artemisinic acid in MCF-7 human breast cancer cells. Various cell signalling pathways (VEGF, m-TOR and AKT signalling pathways) and MTT assay were used. The in vivo ... see more

Apoptotic potential of a-Mangostin (98-99.99% HPLC purified)was evaluated in vitro using MDA-MB-231 human breast cancer cell line as a model system. The nucleosomal DNA gel electrophoresis was performed to delineate the mechanism of a-Mangostin treated MD... see more

The aim of the current study was to investigate the in vitro and in vivo anti-tumor effects of naringenin chalcone in U87MG human glioblastoma cells and in xenograft mice model. The effect of naringenin chalcone on apoptosis induction was assessed by fluo... see more

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