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44.477  Articles
1 of 4.449 pages  |  10  records  |  more records»
The objective of the present work was to enhance the solubility and dissolution rate of valsartan (VAL) a poorly water soluble antihypertensive, by spherically agglomerated solid dispersions using methanol, water and dichloromethane as good solvent, poor ... see more

The poor solubility of drug substances in water and their low dissolution rate in aqueous G.I.T fluid often leads to insufficient bioavailability. As per Biopharmaceutical Classification System (BCS), Olmesartan belongs to the class-II category having poo... see more

Dry fractionation will produce a fraction of olein and stearin with different composition of high melting and low melting as well the distribution of triacylglycerol (TAG) in the form of trisaturated (St3), disaturated (St2U) and monosaturated (StU2). Thi... see more

The study on the posibility of the use of the optimal glass compositions for vitrification of an imitator of vat residues of liquid radioactive waste from nuclear power plants with VVER-1000 reactors was carried out. The main process parameters such as vi... see more

Cocrystallization of mefenamic acid (AM) with para-aminobenzoic acid (PABA) as a coformer has been carried out using the liquid-assisted grinding method. This study aims to determine whether mefenamic acid can be increased its dissolution rate through the... see more

This paper presents a study of operating characteristics of steel 40X10C2M after treatment it of high-energy plasma pulses. The steel is used to manufacture the elements of ships' power plants. For pulsed plasma treatment of steel samples, we used an elec... see more

The increased popularity of deep-fried foods has put health and safety concerns on the agenda. Factors that affect the quality and safety of culinary (frying) fats include the fatty acid profile, as well as cooking modes and time, especially when renewal ... see more

Newly developed single-unit of oral sustained release dosage form for low melting chiral compound, S (+)-ibuprofen have been prepared by the wet granulation method. The hydrophilic matrix was prepared with xanthan gum with additives Avicel PH101. In vitro... see more

Phase field model has been successfully derived from ordinary metal phase field equation to simulate the behavior of semi-crystalline polymer solidification phenomenon. To obtain the polymer phase field model, a non-conserved phase field equation can be e... see more

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