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70  Articles
1 of 7 pages  |  10  records  |  more records»
Rivaroxaban merupakan agen antikoagulan yang mengalami biotransformasi via liver dengan melibatkan peran dari CYP3A4/5 (18%); CYP2J2 (14%) dan sisanya melalui CYP independent hydrolytic cleavage (14%). Polimorfisme yang terjadi pada gen pemetabolisme obat... see more

Rivaroxaban (Xareltoâ), selective direct inhibitor of activated clotting factor Xa belongs to the new oral anticoagulatns (NOACs). Rivaroxaban works to inhibit thrombin formation, and the interruption of the intrinsic and extrinsic pathway of blood coagul... see more

Perdarahan intrakranial spontan pada terapi antikoagulan rivaroxaban mulai sering ditemukan, apalagi bila dikombinasi dengan antiplatelet clopidogrel maupun fibrinolitik lumbrokinase merupakan hal yang sering ditemukan pada penderita trombosis. Perdarahan... see more

In the present investigation it was aimed to evaluate any possible pharmacokinetic interactions between Phenytoin and Rivaroxaban. Study was conducted in Male Wistar rats; animals were divided into three groups. Group 1 received Phenytoin alone, Group 2 r... see more

Foi desenvolvido um modelo de custo-efetividade que compara os custos e consequências associados a rivaroxabano relativamente a enoxaparina na prevenção do tromboembolismo venoso em doentes adultos submetidos a artoplastia eletiva da anca ou joelho. ... see more

Budd-Chiari syndrome (BCS) is the clinical spectrum presenting with hepatic venous outflow obstruction from the hepatic veins to the junction of the inferior vena cava (IVC) and the right atrium. This syndrome is rare in infants and children, which leads ... see more

The secondary prevention after myocardial infarction is aimed to reduce the risk for recurrent cardiovascular events, other complications, and thereby mortality. Despite the emerging guideline-directed pharmacological therapies, certain residual cardiovas... see more



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