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63  Articles
1 of 7 pages  |  10  records  |  more records»
New derivatives of natural compounds, galanthamine using in treatment of  Alzheimer’s disease and antitumor dimer alkaloids vinblastine and vincristine were synthesized. In the course of the reaction between galanthamine and diazomethane in the prese... see more

Background & Objectives: Vincristine has been used as chemotherapeutic agent for many decades. It implements its function by inhibiting the duplication of tumor cells by destroying the DNA. However, like all other drugs, its administration is not with... see more

Vincristine is a preparation of vegetable generation, gotten from the vegetable rose myrtle (Vinca rosea L.), belongs to the group of chemotherapeutic preparations with expressed neurotoxicity. The active use of vincristine in the treatment of malignant t... see more

Background. The increasing incidence of colon malignant tumors is one of the most urgent matters of contemporary medicine. In the study of carcinogenesis of the colon the attention is paid to the state of the body’s immune system and activation of inflamm... see more

ABSTRACT. Ramadinha R.R., Teixeira R.S., Bomfim P.C., Mascarenhas M.B., França T.N., Peixoto T.C., Costa S.Z.R. & Peixoto P.V. [Response of canine transmissible venereal tumor to vincristine sulfate and vinblastine sulfate chemotherapy.] Resposta do tumor... see more

Gastrodia elata Blume (Orchidaceae) is an old traditional Chinese medicine with demonstrated analgesic efficacy in humans. However, the potential analgesic effect of its active component, gastrodin, has not been systematically studied. This work described... see more

Apoptosis or programmed cell death is a mechanism of cell elimination when they are unnecessary or genetically damaged. It is controlled by a variety of genes, many of which present mutation or dysfunstion associated to cancer. When this occurs patients h... see more

Among the more investigated antineoplastic therapeutic options, the anti-angiogenic therapy has no important collateral effects for the patient. This therapy targets the factors implied in the progress of the angiogenic cascade, to impede the vascular sup... see more

Introduction. Every year the number of cancer patients with colorectal cancer is growing. The severity of the condition of patients is often due to hyperfunction of reactive oxygen species with subsequent violation of the body's antioxidant defenses. Ther... see more

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