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60  Articles
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Familial hypocalciuric hypercalcemia (FHH) is an autosomal dominant inherited disorder due to inactivating mutations in the calcium-sensing receptor (CaSR), less commonly in the G-protein subunit a11 (GNA11) or the adaptor-related protein complex 2, sigma... see more

Primary hyperparathyroidism (PHPT) is characterized with primary hyperproduction of parathyroid hormone (PTH) by affected parathyroid glands and with a corresponding increase in concentration of extracellular calcium. Long-term development of PHPT through... see more

Objective: To study the clinical, biochemical and radiological features and management outcomes of patients with primary hyperparathyroidism.Methods: This retrospective study was conducted at the Aga Khan University Hospital, Karachi, Pakistan and compris... see more

Primary hyperparathyroidism (PHPT) is characterized with primary hyperproduction of parathyroid hormone (PTH) by affected parathyroid glands and with a corresponding increase in concentration of extracellular calcium. Long-term development of PHPT through... see more

Background and Aim.Parathyroidectomy is the standard treatment for primary hyperparathyroidism (PHPT). Cinacalcet, an allosteric modulator of the calcium sensing receptor, has been shown to be effective in reducing serum calcium levels and it  has ga... see more

BACKGROUND: The hyperparathyroidism (HPT) is a condition in which the parathyroid hormone (PTH) levels in the blood are increased. HPT is categorised into primary, secondary and tertiary. A rare entity that occurs in the lower jaw in association with HPT ... see more

Primary hyperparathyroidism (PHPT) is the most common cause of  hypercalcemia and is characterized by hypercalcemia and levels of parathyroid hormone (PTH) that are inappropriately high for the hypercalcemic state. The clinical presentation of PHPT h... see more

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