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12  Articles
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BackgroundPediatric nephrolithiasis is an important cause of morbidity worldwide. Even with low prevalence, nephrolithiasis can cause detrimental long-term effects on kidney function. Idiopathic hypercalciuria is the most common cause of renal stones in c... see more

INCIDENCIA DE HIPERCALCIURIA E HIPERURICOSURIA EN PACIENTES PEDIÁTRICOS CON SINTOMATOLOGÍA NEFROUROLÓGICA / INCIDENCE OF HYPERCALCIURIA AND HYPERURICOSURIA IN PEDIATRIC PATIENTS WITH NEPHROUROLOGICAL SYMPTOMS INCIDENCIA DE HIPERCALCIURIA E HIPERURICOSURIA EN PACIENTES PEDIÁTRICOS CON SINTOMATOLOGÍA NEFROUROLÓGICA / INCIDENCE OF HYPERCALCIURIA AND HYPERURICOSURIA IN PEDIATRIC PATIENTS WITH NEPHROUROLOGICAL SYMPTOMSIntroducción: la hipercalciuria y la hiperuricosuria constituyen dos causas importantes de síntomas nefrourológicos en pacientes pediátricos que acuden a las consultas de Nefrología y Urología. Se ha reportado un aumento sostenido de la prevalencia de estos trastornos y los síntomas asociados. Objetivo: mostrar la prevalencia de hipercalciuria e hiperuricosuria en los pacientes que acuden a nuestras Consultas de Nefrología y Urología con síntomas nefrourológicos y la frecuencia de los distintos síntomas que presentaron.Material y métodos: se realizó un estudio retrospectivo analítico de 2770 pacientes a los que se indicó calciuria incluyendo la uricosuria en 2579 de estos, determinándoseles a cada paciente los índices Calcio/Creatinina y Ácido Úrico/Creatinina y estimándose la excreción en 24 horas mediante el modelo matemático elaborado por nuestro grupo.Resultados: de los 2770 pacientes, 1165 (42,05%) presentaron hipercalciuria y 433 (16,8%) hiperuricosuria, y del total en 494 pacientes (17,84%) no se consignaron los datos clínicos. Los síntomas más frecuentes fueron la hematuria, la litiasis, el cólico nefrítico y la infección del tracto urinario en igual proporción, y con menor incidencia se reportaron el dolor abdominal/flanco, la disuria y las fracturas óseas.Conclusiones: la prevalencia de hipercalciuria e hiperuricosuria fue elevada en pacientes con sintomatología nefrourológica sugestiva de estos trastornos; hematuria macroscópica o microscópica, litiasis renal, infección del tracto urinario, cólico nefrítico y en menor proporción dolor abdominal/flanco recurrente, fueron los síntomas más frecuentemente consignados en las indicaciones. Hubo un predominio del sexo masculino en ambos trastornos metabólicos.Palabras clave: hipercalciuria; hiperuricosuria; hematuria; litiasis renal.ABSTRACTObjective: to show the prevalence of hypercalciuria and hyperuricosuria in patients who attend ourNephrology and Urology Consultations with nephrourological symptoms and the frequency of the different symptoms they presented.Method: a retrospective analytical study was carried out of 2770 patients in whom calciuria was indicated,including uricosuria in 2579 of these, determining the Calcium / Creatinine and Uric Acid / Creatinine indicesfor each patient and estimating the excretion in 24 hours by means of the mathematical model developedby our group.Results: of the 2770 patients, 1165 (42.05%) had hypercalciuria and 433 (16.8%) had hyperuricosuria,and of the total in 494 patients (17.84%) the clinical data were not recorded. The most frequent symptomswere hematuria, lithiasis, renal colic, and urinary tract infection in the same proportion, and abdominal /flank pain, dysuria, and bone fractures were reported with a lower incidence.Conclusions: the prevalence of hypercalciuria and hyperuricosuria was high in patients with nephrourological symptoms suggestive of these disorders; Gross or microscopic hematuria, kidney stones, urinary tract infection, renal colic and, to a lesser extent, recurrent abdominal / flank pain, were the symptoms most frequently reported in the indications. There was a male predominance in both metabolic disorders.

Objective: to show the prevalence of hypercalciuria and hyperuricosuria in patients who attend ourNephrology and Urology Consultations with nephrourological symptoms and the frequency of the different symptoms they presented.Method: a retrospective analyt... see more

Dent disease is an x-linked disorder of proximal renal tubular dysfunction that occurs almost exclusively in males. It is characterized by significant, mostly low molecular weight proteinuria, hypercalciuria, nephrocalcinosis, nephrolithiasis, and chronic... see more

Background: The intake of dehydrated nopal (DN) at a high stage of maturity along with high calcium content could improve bone mineral density (BMD) and calciuria and thus prevent osteoporosis. Objective: To evaluate the effect of calcium intake from a ve... see more

Work-up of patients with calcium oxalate stones should be restricted to those who have multiple episodes (50% of stone formers). There are exceptions, such as pilots, fire-workers, people in the armed forces, those with a single kidney and children (<1... see more

Kidney stone disease is one of the most common disorders and can be considered a disease systmetic. It occurs in about 5-20 % of all population. Due to the chemical composition of deposits there are several types of kidney stones including calcium oxalate... see more

Introduction: In paediatric age group urolithiasis is less common with overall occurrence rate of only 2-3% of total cases. Children with urolithiasis are related with significant morbidity. Different metabolic parameters either serum or urinary... see more

Urolithiasis is considered a civilization disease. The prevalence is estimated at 5-20% of the population. There are many litogenesis risk factors such as hypercalciuria, hypophosphaturia, low urine pH or increased excretion of oxalates with urine - a con... see more

Recurrent renal stones occur in 7.5% ofCaucasian men and 3% of all women. Even withincreasing urbanisation, renal calculi are reported inless than I% of black South African men and women. Four hundred recurrent stone formers were studied at the metabolic ... see more

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