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118.979  Articles
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Deciphering the Human Genome is one of the greatest achievements of modern science. The genetic code shows the importance of semiotics in our understanding of evolution. Biosemiotics as the study of signs, communication and information in living organisms... see more

The Human Genome Project has had a significant impact in Medicine. Genomic Medicine is becoming more preventive than curative. The knowledge obtained by the Human Genome Project has allowed the development of genetic diagnostic tests for patients already ... see more

The current human reference sequence (GRCh38) is a foundation for large-scale sequencing projects. However, recent studies have suggested that GRCh38 may be incomplete and give a suboptimal representation of specific population groups. Here, we performed ... see more

Novel therapeutic strategies using genome editing technologies, such as CRISPR-Cas9, are revolutionising the way in which diseases can be prevented and treated in the future. Consequently, a global debate has emerged around the ethical and legal implicati... see more

Can humans control the future evolution of our species? Based on current knowledge in genetics, one can infer and extrapolate what may happen in the near future. After all, if we are to predict the future, we must first understand the foundations of our p... see more

Novel therapeutic strategies using genome editing technologies, such as CRISPR-Cas9, are revolutionising the way in which diseases can be prevented and treated in the future. Consequently, a global debate has emerged around the ethical and legal implicati... see more

One of the major troubles with a comparative analysis between human and other species is that only similar amino acid sequences are selected for analysis. To find the connection among the species and find out the unique, the common and the universal prote... see more

Next-generation sequencing has revolutionized the field of genomics by producing accurate, rapid and cost-effective genome analysis with the use of high throughput sequencing technologies. This has intensified the need for accurate and performance efficie... see more

The elucidation of the human genome constitutes a major paradigm. Besides its impact on our biological nowledge, the elucidation of the human genome will certainly exert a driving force on both medical research and practice in the future. As a paradigmati... see more

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