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8.422  Articles
1 of 843 pages  |  10  records  |  more records»
The concept of Quality by design (QbD) has recently gained importance in the area of analytical method development and involves understanding of the critical factors and their interaction effects by a desired set of experiments. So, the present work descr... see more

Forced degradation studies show the chemical behavior of the molecule which in turn helps in the development of formulation and package. A forced degradation study is an essential step in the design of a regulatory compliant stability program for both dru... see more

The aim of the current research was to make force degradation study of the morpholinium 2-((4-(2-methoxyphenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetate (API) for additional confirmation of the selectivity of API and impurity determination meth... see more

The objective of this study is to isolation and characterization of unknown degradation product of Atorvastatin calcium in combination formulation product with Ezetimibe by using modern techniques of separation and aracterization. An unknown impurity is g... see more

The day by day new combinations drugs are being introduced in market. Then the multiple therapeutic agents which acts at different sites are used in the management of various diseases and disorders are done. Thus it is necessary to develop methods for ana... see more

A new simple, stability- indicating high performance thin layer chromatographic (HPTLC) method has been developed and validated for estimation of Solifenacin succinate in bulk and in tablet dosage form. The optimized mobile phase was Methanol: Water: Glac... see more

A novel and simple reverse phase liquid chromatographic method has been established for the determination of Vildagliptin and Metformin HCl and studies its degradation pattern in pharmaceutical dosage forms. Vildagliptin and Metformin HCl is used to contr... see more

The objective of this study was to develop the degradation studies of different brands of Flunarizine dihydrochloride tablet available in market. Forced degradation is a process that involves degradation of drug products and drug substances at conditions ... see more

A novel and simple reverse phase liquid chromatographic method has been established for the determination of Sitagliptin and Metformin HCl and studies its degradation pattern in pharmaceutical dosage forms. Sitagliptin and Metformin HCl is used to control... see more

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