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3.283  Articles
1 of 329 pages  |  10  records  |  more records»
Infection through the Hepatitis C virus does not have a vaccine and treatment with pegylated interferon and ribavirin can fail; which is why it may cause chronic infection and, consequently, could develop liver failure or hepatocellular carcinoma. It has ... see more

Extracts from Origanum majorana L. are used in Asia and Africa as sedatives and neurotonics. Few studies done to explore the active chemical constituents responsible for this apparent contrast. The inhibitory glycine receptors (GlyRs) are key mediators of... see more

Tarczykowska Agata, Kochanski Bartosz, Wolowiec Lukasz, Surowiec Agnieszka, Plaskiewicz Anna, Zukow Walery. Ocena skutecznosci i bezpieczenstwa farmakoterapii inhibitorami aldosteronu w niewydolnosci serca = Evaluation of the efficacy and safety of pharma... see more

Treatment couples with a combination of male and female factor infertility is the most difficult and often requires precisely ART. However, ICSI efficacy currently does not exceed 35-40 %, about a third of all pregnancies are terminated early. The purpos... see more

Despite a perpetual increase in the prevalence of benign lymphoepithelial lesion, data on the mechanisms governing its pathogenesis are still missing. Thus, we aimed in the present study to evaluate whether TLRs could regulate the expression of the pleiot... see more

Tumour necosis factor alpha (TNF-?) is known to be involved in pathogenesis of acute renal allograft rejection. However, measurement of cytokine serum levels alone are not a reliable index of acute rejection episodes. TNF-?induces the release of soluble r... see more

Development of effective treatment agents for the alcohol use disorders requires the detailed understanding of molecular targets of alcohol in the brain. The gamma-aminobutyric acid type A receptors (GABAARs) are the major molecular targets of alcohol in ... see more

Altered regulation of the cell cycle and/or apoptosis are well established events in the process of neoplastic transformation. Fas-mediated apoptosis is regulated by several inhibitory proteins in normal lymphocytes and leukemic cells. Some of these prote... see more

Tricyclic antidepressants and serotonin noradrenaline reuptake inhibitors are used to treat chronic pain, such as neuropathic pain. Why antidepressants are effective for treatment of neuropathic pain and the precise mechanisms underlying their effects, ho... see more

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