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49.162  Articles
1 of 4.917 pages  |  10  records  |  more records»
Prospects for the search of antiviral agents among 4-thiazolidinone derivatives, as well as the optimal directions of the main core structure optimization – namely C5 and N3, have been described. As the result of the screening performed (within ... see more

Calixarenes is a promising class of macrocyclic compounds, which are widely used in the design of biologically active substances. Among calixarenes there are anion channel blockers and modulators of cationic pumps, selective enzyme inhibitors and compound... see more

Alkylation of potassium 9-R1-10-R2-3-R-2-oxo-2?-[1,2,4]triazino[2,3 ?]quinazolin-6-thiolates by N-cycloalkyl-(cycloalkylaryl-)-2-chloracetamides and interaction of [(9-R1-10-R2-3-R-2-?xo-2H-[1,2,4]triazino[2,3-?]quinazolin-6-yl) thio]aceti? acids imidazol... see more

Aim. To synthesize, prove the structural framework and study the antiviral activity of 1-(4-chlorophenyl)-4-(para-tolyl)-5,6,7,8-tetrahydro-2a,4a-diazacyclopenta[cd]azulene-2-carboxylic acid derivatives.Results and discussion. The antiviral activity of 1-... see more

Serum pathogen-free (SPF) embryonated egg for culturing virus has three main steps: a) candling of egg, b) inoculation of egg and c) harvesting of inoculated egg. Furthermore, hemagglutination assay consists of only one step. The method is easy to perform... see more

Medicinal plant extracts have a broad antimicrobial activity, including antiviral effects. In our study, eleven dry extracts of ten different medicinal plants prepared with two solvents (5%, dimethyl sulfoxide (DMSO) and 30% ethanol in 5% DMSO) in differe... see more

The present study evaluates the antiviral activity of banana lectin (BanLec) against herpes simplex virus type 1 and 2 (HSV-1 and HSV-2). Lectin was isolated from the ripen pulp of bananas (Musa paradisiaca). The study showed that lectin exhibited hemaggl... see more

In the present work, it was shown that, in non-toxic concentrations, all EPSs which were isolated from lactic acid bacteria have significant anti-HSV-1 activity affecting various stages of the virus reproduction. It was demonstrated that the use of ESPs l... see more

The medicinal plants have played a vital role in drug discovery. Many plants are used traditionally for the treatment of different types of viral disorders and other infectious diseases. Herpes simplex virus (HSV) is a ubiquitous organism that causes infe... see more

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