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51  Articles
1 of 6 pages  |  10  records  |  more records»
Content of peculiarities of basic anti-inflammatory therapy and its efficacy in children with available or absent deletion polymorphism of GSTM1  and GSTT1genes coding II phase enzymes of GSTM1 and GSTT1xenobiotic detoxication considering their ... see more

Objectives: To explore the association of genetic polymorphisms in individual or combined genotypes of GSTM1, GSTT1 and GSTP1 with cervical cancer (CC) susceptibility in women from Maharashtra.Methods: The polymorphisms in GSTM1 and GSTT1 were analyzed by... see more

BACKGROUND: Glutathione S-transferase Mu-1 (GSTM1) is known to undergo polymorphism and plays role in drug metabolism including Paclitaxel (PTX), the first-line chemotherapy for breast cancer. However, the effect of GSTM1 polymorphism against chemotherapy... see more

BACKGROUND: Glutathione S-transferase Mu-1 (GSTM1) is known to undergo polymorphism and plays role in drug metabolism including Paclitaxel (PTX), the first-line chemotherapy for breast cancer. However, the effect of GSTM1 polymorphism against chemotherapy... see more

Introdução: Os cânceres de tireoide são doenças multifatoriais, derivadas do epitélio folicular e de células C parafoliculares. A deleção dos genes das glutationas-S-transferase, theta (GSTT1) e mu (GSTM1), pode reduzir a capacidade das células em desinto... see more

Colorectal cancer (CRC) is one of the most common malignancies. Susceptibility to malignant processes is mediated by genetically driven differences in the effectiveness of detoxification of potential carcinogens. One of the factors that may influence the ... see more

The aim of the research. To investigate the association of the development of primary open-angle glaucoma with deletion polymorphism of glutathione-S-transferase genes.Materials and methods. Under our observation there were 172 patients, residen... see more

Resumo: endometriose é a presença funcional das glândulas estromais do endométrio fora da cavidade uterina. O resultado do teste do x2, foi significativo (p=0,0049), encontrando maior ausência dos genes GSTM1 e GSTT1 no grupo sem endometriose comprovada.P... see more

Resumo: o polimorfismo do gene de codificação enzimática na fase de detoxificação de agentes carcinogênicos pode alterar a eficiência do biometabolismo de agentes potencialmente genotóxicos. O objetivo do presente estudo foi avaliar o polimorfismo do gene... see more

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