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35.708  Articles
1 of 3.572 pages  |  10  records  |  more records»
An important issue of modern medicine is the pharmacological correction of regulatory mechanisms of the excretory renal function aimed to normalize the changed water-electrolytic balance in a diseased body. In order to establish the functional balance and... see more

The intensive and purposeful search of fundamentally new diuretics conducted by our research laboratory among the derivatives of 4-hydroxyquinolin-2-ones has found 7-hydroxy-5-oxo-2,3-dihydro-1H,5H-pyrido[3,2,1-ij] quinoline-6-carboxylic acid 2-carboxyani... see more

Aim – the search for biologically active compounds with diuretic and hypoglycemic action among 7-substituted of 3-benzyl-8-propylxanthines, which can be used for the treatment of pathologies of “metabolic syndrome”.Materials and methods. 30 new ... see more

Introduction. Prolonged usage of diuretics, especially in large doses, the number and severity of side effects (water-electrolyte and metabolic disorders), as well as the relatively limited range of existing diuretics dictate the need to find new compound... see more

Topicality. The problems of inflammatory diseases of kidneys and urinary tract are some of the most difficult in the modern urology. The necessity for long-term use of drugs in the conservative treatment of non-specific inflammatorydiseases of the urogeni... see more

Acute renal failure is one of the most severe conditions of kidney damage. This syndrome is characterized by a sharp decrease in excretory renal function with azotemia and significant violations of water-salt homeostasis, which causes the use of diuretics... see more

Diuretics are widely used to correct kidney disorders. In turn, the ionic composition of food, mostly sodium ions, which directly affect the excretory function of the kidneys, can act as modulators of the action of diuretics.The aim of the study was to in... see more

Aim – the search for biologically active compounds with diuretic and hypoglycemic action among 7-substituted of 3-benzyl-8-propylxanthines, which can be used for the treatment of pathologies of “metabolic syndrome”.Materials and methods. 30 new chemical c... see more

EXPERIMENTAL RESEARCH DIURETIC PROPERTIES OF NEW 7-METHYL-N-BENZYL-8-SUBSTITUTED THEOPHYLLINE.Matviychuk O.P., Gladchenko O.M., Matviychuk A.V., Ivanchenko D.G.National University of PharmacyZaporozhye State Medical UniversityIntroduction.  Diuretics... see more

1 of 3.572 pages  |  10  records  |  more records»