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197  Articles
1 of 21 pages  |  10  records  |  more records»
Emotional dysregulation in early childhood has shown various early symptoms, such as aggressiveness, anxiety, short attention span, etc. This study aims to determine the effects of family cohesion, interpersonal communication, and smartphone addiction var... see more

Autism spectrum disorder (ASD) is a devastating disease affecting 1 in 68 children in the United States. Although much has been learned, the etiology and pathogenesis of autism remain largely elusive. More recently, mutations or variants of genes encoding... see more

This article aims to investigate the association between emotion dysregulation and alcohol related intimate partner violence. A systematic review was conducted through a literature research for relevant studies on Medline, CINAHL Plus with Full Text, Psyc... see more

Background: Borderline Personality Disorder (BPD) is mostly characterized by emotional dysregulation manifested in subjective, behavioral, and physiological terms. Although, a huge number of studies conducted on this topic, empirical findings remain mixed... see more

 
Accumulating evidences have shown that miRNA dysregulation occurs in the majority of human malignancies. This study aims to identify miRNAs that are involved in the cellular senescence pathway through in-silico approach. Two different bioinformatics appro... see more

This research aims to explore the emotional dysregulation in employees with Allergic Rhinitis (AR) from the employee's perspective. This study used a mixed-method with an explanatory sequential design. The subjects of this study were sixty productive age ... see more

Introduction. Covid-19 pandemic negatively influenced daily life and psychological well-being on global population. Since conditions of emotional distress appear to underlie non-suicidal self-injury (NSSI) episodes, particularly for individuals with diffi... see more

Background: Disturbance of circadian rhythm leads to abnormalities in bile acid (BA) and lipid metabolism, and it is of great significance to explore the relationship between them. This study explored the effects of circadian dysregulation on the rhy... see more

Aproximación a la dinámica de la respuesta inmune en la infección por la COVID-19 / Approach to the dynamics of the immune response in the COVID-19 infection Aproximación a la dinámica de la respuesta inmune en la infección por la COVID-19 / Approach to the dynamics of the immune response in the COVID-19 infectionObjetivo: caracterizar las particularidades de la dinámica de larespuesta inmune durante la infección por la COVID-19.Desarrollo: el sistema inmune juega un papel en la patogeniade la COVID-19 en el que el infiltrado de neutrófilos es un eventoimportante durante la enfermedad. La producción de citocinasproinflamatorias por activaciones anómalas de las vías deseñalización y desregulación en los interferones, son mecanismosinvolucrados en la respuesta inmune de esta enfermedad. Estasevidencias justifican el uso de tratamientos inmunosupresorescomo la metilprednisolona en los pacientes con cuadros graves. Larespuesta inmune adaptativa aparece después de las dos semanasde infección, aunque la IgM se detecta desde la primera semana.La respuesta de los linfocitos T es indispensable en la completaeliminación de la infección viral.Conclusiones: el sistema inmune juega un papel importanteen la destrucción del epitelio alveolar y el desarrollo de lossíntomas graves de la COVID-19, de ahí que los tratamientosinmunomoduladores pueden beneficiar a estos pacientes.Palabras clave: COVID-19; coronavirus; respuesta inmune;inmunopatogenia.ABSTRACTObjetivo: to characterize the peculiarities of the dynamics of theimmune response during infection with COVID-19.Development: the immune system plays a role in the pathogenesisof COVID-19, where the neutrophil infiltrate is an important eventduring the disease. The production of proinflammatory cytokinesby abnormal activations of the signaling and dysregulationpathways in interferons are mechanisms involved in the immuneresponse of this disease. These evidences justify the use of immunosuppressive treatments such as methylprednisolone inpatients with severe symptoms. The adaptive immune responseappears after two weeks of infection, although IgM is detectedfrom the first week. The response of T lymphocytes is essential inthe complete elimination of the viral infection.Conclusions: the immune system plays an important role inthe destruction of the alveolar epithelium and the developmentof severe symptoms of COVID-19, hence immunomodulatorytreatments can benefit these patients.Keywords: COVID-19; coronavirus; immune response;immunopathogenesis.

respuesta inmune durante la infección por la COVID-19.Desarrollo: el sistema inmune juega un papel en la patogeniade la COVID-19 en el que el infiltrado de neutrófilos es un eventoimportante durante la enfermedad. La producción de citocinasproinflamatoria... see more

1 of 21 pages  |  10  records  |  more records»