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40.208  Articles
1 of 4.022 pages  |  10  records  |  more records»
Objectives: To determine the frequency of endocrine disorders in Beta-Thalassemia Major (BTM) patients presenting for Endocrine Evaluation to the Department of Diabetes, Endocrinology and Metabolic Diseases, Hayatabad Medical Complex, Peshawar, Pakistan, ... see more

Growth disorders in short stature are often found in patients with ß-thalassemia major. It is caused by several factors such as hypoxia, hemosiderosis, deficiency of nutritional intake, and micronutrient. Disorder in growth will affect the patient's quali... see more

Beta-thalassemia major (BTM) is difficult to treat chronic disease, causing physical and psychological burdens for the patient. Several studies have confirmed a decrease in physical activity and depression in thalassemia patients, but limited studies exam... see more

Thalassemia is a chronic disease with long-term treatment that increases the potential for impact on physical, cognitive, and psychological conditions. About 80% of patients with major thalassemia have at least one psychiatric disorder, depression is one ... see more

Natural killer (NK) cells act both as cytotoxic and cytokine producers in the innate immune response. Hyperferritinemia resulting from a routine blood transfusion as a specific treatment in major ß-thalassemia patients may disturb the cellular immune syst... see more

Thalassemia beta major is a hereditary hemolytic anemia disease with various grades of severity, which can be found with no or less globin chain qualitative synthesis. The patient often experiences hepatosplenomegaly, growth retardation and bone disorder ... see more

Beta major thalassemia is a genetically inherited blood disorder due to a genetic mutation on the polypeptide chains of hemoglobin which is manifested in the growth and development of the tooth. The objectives of the investigation were to obtain differenc... see more

Background: Cardiac complications are the major cause of mortality and morbidity in thalassemic children. Iron deposition inmyocardium is the key factor leading to poor cardiac functions. Myocardial performance index (MPI) by echocardiography (ECHO)can be... see more

 Background: Cardiac hemosiderosis in major thalassemia has a high mortality rate. Serum ferritin levels are routinely performed to measure body iron deposit Early detection of cardiac dysfunction by routine echocardiography is very important to prev... see more

1 of 4.022 pages  |  10  records  |  more records»