SUMMARY
Uncertainty of social and economic processes increases in the current economic environment, which complicates management of the economic systems and leads to an increase in risks. Under similar conditions a search of new approaches and management principles ensuring increase in flexibility and competitiveness of transport infrastructure projects is necessary. A synergistic approach in the management of the complex projects is aimed at the innovative breakthrough and sustainable development of the economic systems taking into account the requirement of the maximum satisfaction of the market needs at coordination of resources. The article substantiates topicality of synergistic management of transport infrastructure projects for the innovative development and the possibility to get positive synergistic and complementary effects. The fundamentals of synergistic management are defined. A synergistic model of the sequential and interconnected actions of all participants of megaprojects presenting a system of instruments of elaboration and implementation of priorities of infrastructure projects and transport sphere programs is formed.