ARTICLE
TITLE

Polymorphism in the gene FABP3 and its association with indicators of meat quality in pigs

SUMMARY

Received: 2016-06-07 | Accepted: 2016-06-16 | Available online: 2016-12-22http://dx.doi.org/10.15414/afz.2016.19.04.171-173The objective of this study was to analyze the variability of the FABP3 gene (heart fatty acid-binding protein) in the population ofpig Czech large white breed and to analyze the association with parameters of meat quality. FABP3 belongs to multigene familyof FABPs (fatty acid binding proteins affecting the transport of long chain fatty acids). Analyzed polymorphism was at positionX98558:g.1321 G > C in the 5’ UTR region. The relative frequencies of genotypes were: HH = 0.87and Hh = 0.13. Genotype hh wasnot detected in the population. The frequencies of alleles were as follows: H = 0.93 and h = 0.07. There were statistically significantassociations between genotypes and values of stearic acid and linoleic acid. Highly statistically significant difference was observedwith palmitic acid.Keywords: SNP polymorphism, FABP3, pig, fatty acidsReferencesFERNANDEZ, X. et al. (1999) Influence of intramuscular fat content on the quality of pig meat. Composition of the lipid fraction and sensory characteristics of m. longissimus lumborum. Meat Sci, vol. 53, pp. 59–65.HAN X.et al. (2012) Investigation of four porcine candidate genes (H-FABP, MYOD1, UCP3 and MASTR) for meat quality traits in Large White pigs. Molecular Biology Reports, vol. 39, pp. 6599–6605.CHMURZYNSKA, A. (2006) The multigene family of fatty acid-binding protein (FABPs): Function, structure and polymorphism. Journal of Applied Genetics, vol. 47, no.1, pp. 39-48.MAHARANI, D. et al. (2012) Evaluation of Three Candidate Genes Affecting Fatty Acid Composition in Pigs. Korean Journal for Food Science of Animal Resources, vol. 32, pp. 6–12.PANG, W.J., BAI, L. and YANG G.S. (2006) Relationship among H-FABP gene polymorphism, intramuscular fat content, and adipocyte lipid droplet content in main pig breeds with different genotypes in western China. Acta Genetica Sinica, vol. 33, no. 6, pp. 515–524.REARDON, W.et al. (2010) Association of polymorphisms in candidate genes with colour, water-holding capacity, and composition traits in bovine M. longissimus and M. semimembranosus. Meat Sci, vol. 86, no. 2, pp. 270–275.TYRA, M.et al. (2010) H-FABP and LEPR gene expression profile in skeletal muscles and liver during ontogenesis in various breeds of pigs. Domestic Animal Endocrinology, vol. 40, pp. 147–154.WANG, W. et al. (2013) Candidate gene expression affects intramuscular fat content and fatty acid composition in pigs. Journal of Applied Genetics, vol. 54, no. 1, pp. 113–118.

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