SUMMARY
Antihistamines Loratadin available in tablet form, as loratadin tablets innovator, branded generic preparations. Socializing generic drugs need information about quality of these drugs, to ensure that the quality of generic drugs not lower or similar to its innovator drugs. The impact of economic crisis caused the price of very expensive drugs. The information quality of generic drugs is expected to increase the use of generic drugs by health practitioners and public. It is necessary for the laboratory data that are qualityparameters, such as dissolution profiles, dissolution testing and determinationof drug dosage levels. Dissolution test method anddetermination of levelsconducted in accordanceto the requirements of the USP (United State of Pharmacopeia). Loratadin dissolution test resultsof tablets A, B and Cin accordancewith the requirements of the USP. Loratadin contentin tablet Ais 103, 73%, B=99,62% and C=100,21%. Loratadin levels in all of these tablets meet the requirements of the USP. Key words: innovator,branded generic drug, dissolution, content